Background: To improve the athletic ability and muscle mass, anabolic androgenic steroids are abused by athletes. Little is known about how these compounds affect the fine structures of the testis. This study aimed to identify the changes in the fine structure of testis following administration of nandrolone decanoate. Methods: Twenty five Sprague-Dawley rats were randomly divided into two expe...

conclusions the findings suggest that chronic coadministration of nandrolone with moderate-intensity endurance exercise facilitates the vf occurrence in rat. complementary studies are needed to elucidate the involved mechanisms of this abnormality. results nandrolone, exercise, and their combination were associated with heart hypertrophy. exercise could prevent the incremental effect of nandrol...

background: to improve the athletic ability and muscle mass, anabolic androgenic steroids are abused by athletes. little is known about how these compounds affect the fine structures of the testis. this study aimed to identify the changes in the fine structure of testis following administration of nandrolone decanoate.   methods: twenty five sprague-dawley rats were randomly divided into two ex...

Changes in the number and size of oocytes can lead to fertilization problems. The present study aimed to evaluate the number, volume, and surface area of oocytes in healthy as well as nandrolone decanoate-treated (ND) mice using stereological methods. Five control mice received vehicle, and five ND-treated mice received ND. Using the 'isotropic Cavalieri' design', the ovary was sectioned. The v...

AIM To investigate the reversibility of the effect of nandrolone decanoate (ND) on sperm parameters after discontinuing the drug. METHODS Three groups of rats received peanut oil (control), low and high doses of ND for 14 weeks, respectively. Each group was divided into subgroups A and B, in which rats were killed 14 and 28 weeks after initiating the injection, respectively. RESULTS Sperm c...

Highly satisfactory results obtained with improvement was seen in two still under 50 mg./week nandrolone decanoate treatment. Once therapy had been com(Deca-Durabolin) for 3-16 months are menced, there was a period of latency reported in 10 cases of aplastic anemia. which fluctuated between 1 and 9 In the series thus treated there were only months. Except for one patient with two deaths, occurr...

BACKGROUND To date, no studies document the effect of anabolic steroids on rotator cuff tendons. STUDY DESIGN Controlled laboratory study. HYPOTHESIS Anabolic steroids enhance remodeling and improve the biomechanical properties of bioartificially engineered human supraspinatus tendons. METHODS Bioartificial tendons were treated with either nandrolone decanoate (nonload, steroid, n = 18), ...

Nandrolone is included in the class II of anabolic androgenic steroids (AAS) which is composed of 19-nor-testosterone-derivates. In general, AAS is a broad and rapidly increasing group of synthetic androgens used both clinically and illicitly. AAS in general and nandrolone decanoate (ND) in particular have been associated with several behavioral disorders. The purpose of this review is to summa...