background: chitosan nanoparticles have become of great interest for nanomedicine, biomedical engineering and development of new therapeutic drug release systems with improved bioavailability, increased specificity and sensitivity, and reduced pharmacological toxicity. the aim of the present study is to synthesis and optimization of chitosan nanoparticles for industrial and biomedical applicati...

patient noncompliance to current tuberculosis (tb) therapy owing to multidrug administration daily leads to treatment failure and emergence of multidrug resistant and extensively drug resistant tb. to avoid the daily dosing, application of nanotechnology is the only viable solution by virtue of sustained release of drugs. other potential advantages of the system include the possibility of selec...

Nanomedicine provides a unique opportunity for promoting drug efficacy through enhanced delivery mechanisms. However, its translation into the clinics has been relatively slow compared with the large amount of research occurring in laboratory settings. Given the limitations of conventional cell culture models and preclinical animal models, we discuss the potential utility of recently developed ...

Lately, nanotechnology and nanomedicine have achieved tremendous interest and funding, from several entities and directions. Nanomedicine demonstrates great promise for development of medical diagnosis, treatment, and prevention; it also raises various ethical concerns however, there has not been so much study and discussion about social and ethical issues. Nanomaterials are extremely reactive ...

Medical practice is about to enter a new era focused on the nanoscale and the practice of nanomedicine, defined as the monitoring, control, construction, repair, defense, and improvement of human biologic systems via engineered nanodevices and nanomaterials. The potential impact of nanomedicine on society is expected to be huge as the nanopharma market grows significantly in the coming years. G...

A novel sandwich nanomedicine (GO-BNN6) for near-infrared (NIR) light responsive release of nitric oxide (NO) has been constructed by self-assembly of graphene oxide (GO) nanosheets and a NO donor BNN6 through the π-π stacking interaction. The GO-BNN6 nanomedicine has an extraordinarily high drug loading capacity (1.2 mg BNN6 per mg GO), good thermal stability, and high NIR responsiveness. The ...

What is the real commercial potential for nanotechnology and, in particular, nanomedicine? Depends on your definition. For example, if you think nanomedicine refers to Michael Crichton's self-replicating nanorobots traversing the body and healing disease (as in his 2002 novel Prey), I bet you will be waiting a long time (if ever) to see commercial fruition. On the other hand, if you envision na...

Nanomedicine, the use of nanotechnology for biomedical applications, has potential to change the landscape of the diagnosis and therapy of many diseases. In the past several decades, the advancement in nanotechnology and material science has resulted in a large number of organic and inorganic nanomedicine platforms. Silica nanoparticles (NPs), which exhibit many unique properties, offer a promi...

Recent developments in polymer-based controlled delivery systems have made a significant clinical impact. The second Symposium on Innovative Polymers for Controlled Delivery (SIPCD) was held in Suzhou, China to address the key challenges and provide up-to-date progress and future perspectives in the innovation of polymer-based therapeutics. At SIPCD, a stimulating panel discussion was introduce...