نتایج جستجو برای: navab
تعداد نتایج: 81 فیلتر نتایج به سال:
Structure of a bacterial voltage-gated sodium channel pore reveals mechanisms of opening and closing
Voltage-gated sodium channels are vital membrane proteins essential for electrical signalling; in humans, they are key targets for the development of pharmaceutical drugs. Here we report the crystal structure of an open-channel conformation of NavMs, the bacterial channel pore from the marine bacterium Magnetococcus sp. (strain MC-1). It differs from the recently published crystal structure of ...
A Key Gating Charge Interaction Required for Slow Inactivation of the Navab Bacterial Sodium Channel
this paper reports five cases of neuroleptic malignant syndrome, admitted to shahid navab safavi psychiatric center during a period of six months. the onset and course of syndrome, types of drugs prescribed, and the variety of symptoms, were studied. results showed that early diagnosis of the syndrome, cessation of neuroleptic drugs, and classical treatment were efective in saving the lives of ...
Background and Objectives: ?????? Methods: ?????? Findings: ?????? Conclusion: ????? The present study is the first study aimed at biostratigraphy based on calcareous nannoplankton that has been performed on all succession exposed from the Oligo-Miocene marine deposits (members a to f of the Qom Formation). The studied deposits are located in the middle part of the Central Iran Zone and m...
Verreth, Dominique Stengel, Ewa Ninio, Mohamad Navab, Bharti Mackness, Mike Mackness Ann Mertens, Peter Verhamme, John K. Bielicki, Michael C. Phillips, Rozenn Quarck, Wim Atherosclerosis Atherosclerosis in Dyslipidemic Obese Mice : LCAT Gene Transfer Decreases Antioxidant Defense Are Associated With Increased Macrophage Homing and Increased Low-Density Lipoprotein Oxidation and Impaired High-D...
The S4 helix of voltage sensor domains (VSDs) transfers its gating charges across the membrane electrical field in response to changes of the membrane potential. Recent studies suggest that this process may occur via the helical conversion of the entire S4 between α and 310 conformations. Here, using LRET and FRET, we tested this hypothesis by measuring dynamic changes in the transmembrane leng...
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