purpose: to report two cases of granulomatosis with polyangiitis (gpa) presented ocular manifestations. cases report: we report two cases of scleritis with red eye, one of them was a 30 years old female patient with saddle nose and positive c-anca and the other one was a 56 year-old female patient with lung cavitation and positive c-anca. both cases undergone corticosteroid and immunosuppressiv...

We report the history and clinical presentation of an 88-year-old female with Fuchs dystrophy who developed an acute anterior necrotizing scleritis in her left eye 23 months after an uncomplicated combined penetrating keratoplasty and phacoemulsification with intraocular lens implantation which progressed to slceral perforation with uveal prolapses. The patient underwent a complete systemic wor...

Rheumatoid arthritis (RA) is a systemic inflammatory disease associated with a number of extra-articular organ manifestations. Ocular manifestations involved with RA are keratoconjunctivitis sicca, episcleritis, scleritis , corneal changes, and retinal vasculitus. The etiopathogenesis of this autoimmune disorder is still unknown. Aim of our study was to present different ocular manifestations o...

The authors present a case of Wegener’s granulomatosis that had as first symptom scleritis, uveitis and proptosis. Because of rapidly progressive glomerulonephritis, the patient was admitted three months later. On the 12 day, third of cyclosphosphamide therapy, the patient died in respiratory distress. Autopsy disclosed focal and segmental necrotizing glomerulonephritis with crescent formation,...