background and objectives: resistance to macrolide can be mediated by erm and msra genes in staphylococcus aureus . there are the evidences that show erm genes may be causative agent of inducible or constitutive resistance. the aim of this study was to investigate the incidence of inducible clindamycin resistance and determine the most frequency of erm and msr a genes among s. aureus isolates. ...

introduction: drug resistant staphylococci are the most important agents of nosocomial infections. in this survey, effect of different antibiotics on these bacteria and their drug resistance was investigated. methods: the study included 500 strains of staphylococci. minimum inhibitory concentrations of all antibiotics was determined by the broth macro dilution technique and standard methods fro...

background: lower respiratory tract infections are among important causes of morbidity and mortality for all age groups. the emergence of multidrug resistant gram-negative bacilli is an issue of increasing concern. materials and methods: a retrospective study including respiratory specimens (sputum and bal) was conducted in our tertiary care centre. samples were processed for microscopy, cultur...

antimicrobial resistance in pathogens not only in hospitals but also in the community has become an important public health problem. the aim of this study was to determine the antimicrobial resistance patterns of predominant pathogens from hospitalized and outpatients in a university hospital in tehran, iran. a total of 820 samples of common gram-negative and gram-positive bacteria were collect...

background and objectives: macrolide, lincosamide and streptogramin b (mlsb) antimicrobial agents are widely used in the treatment of staphylococcal infection. clindamycin is the medicine of choice for some staphylococcal infections, particularly skin and soft tissues infections. erythromycin and clindamycin are two distinct classes of antimicrobial agents which inhibit protein synthesis in bac...

Introduction: Diffusion of antibiotic resistance genes by horizontal gene transfer has led to the fast emergence of multidrug resistance (MDR) among bacteria. Multiple classes of integrons are effective genetic elements which play a significant role in the acquisition and nosocomial dissemination of resistance factors in strains of Gram-negative bacteria, Pseudomonas aeruginosa, and Acinetobact...

conclusions based on our findings, p. aerugionsa is a major causative agent of wound infections and amikacin could be considered as a more effective antibiotic for treatment of the burned patients. background nowadays, the treatment of burned patients is difficult because of the high frequency of infection with antibiotic resistance bacteria. objectives this study was conducted to evaluate the ...