neonatal sepsis, a life-threatening condition, presents with non-specific clinical manifestations and needs immediate empirical antimicrobial therapy. choosing an appropriate antibiotic regimen covering the most probable pathogens is an important issue. in this study we compared the effectiveness of ceftizoxime and amikacin in the treatment of neonatal sepsis both in combination with ampicillin...

In this report, a new series of fluoroquinolone agents which was derived from levofloxacin was synthesized and evaluated against Gram-positive (Bacillus subtillis, Staphylococcus aureus, Staphylococcus epidermidis and Micrococcus luteus) and Gram-negative (Esherichio coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Serratia marcescens) organisms. The results showed that some of the synth...

INTRODUCTION Staphylococcus lugdunensis is an unusually virulent coagulase-negative staphylococcus that has rarely been implicated in central nervous system infections. CASE PRESENTATION Two children hospitalized in the Neurosurgery Unit developed ventriculitis caused by methicillin-resistant Staphylococcus lugdunensis following placement of external ventriculostomy drains. The causative orga...

given the inappropriate use of antibiotics and prevalence of resistant bacteria, there is urgentneed for antibacterial drugs that have fewer side effects than antibiotics. satureja bachtiaricais a medicinal plant which had many uses in traditional medicine. in this research, the ethanolextract of leave of satureja bachtiarica is tested on coagulase-negative staphylococcus strains.materials and ...

AIM This study was devoted to elucidate the tetracycline resistance of coagulase-negative staphylococci (CNS) derived from normal and subclinical mastitic (SCM) buffaloes' milk in Egypt. MATERIALS AND METHODS A total of 81 milk samples from 46 normal buffalo milk samples and 35 SCM buffalo milk samples at private dairy farms of Egypt were used in this study. CNS were identified using phenotyp...

background and objective: antibiotic resistance is increasing, especially in healthcare-associated infections causing significant public health concerns worldwide. national information is required to make appropriate policies, update list of essential drugs for treatment, and evaluate the effects of intervention strategies. a nationwide surveillance of antimicrobial resistant bacteria in nosoco...

A bacteriological study of external ear canal was performed in 52 hospitalized cancer patients and 42 non hospitalized cancer patients at Shafa hospital, Ahwaz. Study was under taken to find out the normal flora changes in the external ear canals and to observe the prevalence of external otitis among these cancer patients. The control group consisted of 40 non-cancer patients. We observed the f...

Staphylococcus schleiferi is a new species of coagulase-negative staphylococcus first described in April 1988 (J. Freney, Y. Brun, M. Bes, H. Meugnier, F. Grimont, P. A. D. Grimont, C. Nervi, and J. Fleurette, Int. J. Syst. Bacteriol. 38:168-172, 1988). There are few data in the literature on its pathogenicity. We report two cases in which its role as an opportunistic nosocomial appears to be i...