The potential exposure to ribavirin aerosol in the environment was assessed in nurses caring for infants and children with severe lower respiratory tract infections due to respiratory syncytial virus. Ribavirin aerosol was administered via a ventilator, oxygen tent, or oxygen hood. Participants worked directly with infants receiving ribavirin for 20.0 to 35.0 h over a 3-day period. No toxic or ...

Hereditary osteo-onychodysplasia (HOOD, nail-patella syndrome) is an autosomal dominant condition characterised by nail dysplasia, patellar hypoplasia or aplasia, and nephropathy. The risk for HOOD patients to have a child with HOOD who will develop renal failure cannot easily be deduced from published pedigrees. We have studied a large family with 30 patients with HOOD and have analysed 34 kin...

vessel for microanastomosis, non-microsurgical methods are suggested, such as a composite graft, retroauricular pocket, or a temporoparietal fascia flap. A few reports of large composite grafts to the ear have been published. The survival rate of composite grafts is lower than that of replantation with microvascular anastomosis. The vessel status of amputees who have sustained a human bite inju...

Prenatal stress in rats results in structural, physiological and behavioral alterations that persist in adulthood. Serotonin (5-HT) is an important neurotransmitter known to be involved in these prenatal stress-induced behavioral alterations. The aim of the study was to investigate the effects of interrupted synthesis of 5-HT and immobilization stress during different gestational period on brai...

BACKGROUND Sleeping metabolic rate (SMR) is used as a proxy for basal metabolic rate in infants, when measurement while awake is not practical. Measuring SMR via indirect calorimetry (IC) can be useful for assessing feeding adequacy especially in compromised neonates. Standard IC equipment, including a hood placed over the head, is not designed for the smallest of patients. Our aim was to deter...

OBJECTIVE To measure the delivered fractional oxygen concentration (F(DO(2))) from preterm-size Laerdal silicone resuscitators (PLSR) without a reservoir. BACKGROUND The North American Neonatal Resuscitation Program manual states that self-inflating bags without a reservoir deliver approximately 40% oxygen, differing from the PLSR manufacturer's specifications. METHODS A neonatal test lung ...

OBJECTIVE To evaluate the effects of various flow rates of oxygen administered via 1 or 2 nasal cannulae on the fraction of inspired oxygen concentration (FIO2) and other arterial blood gas variables in healthy neonatal foals. ANIMALS 9 healthy neonatal (3- to 4-day-old) foals. PROCEDURES In each foal, a nasal cannula was introduced into each naris and passed into the nasopharynx to the lev...

Hyperbaric oxygen therapy for the treatment of neonatal hypoxic-ischemic brain damage has been used clinically for many years, but its effectiveness remains controversial. In addition, the mechanism of this potential neuroprotective effect remains unclear. This study aimed to investigate the influence of hyperbaric oxygen on the proliferation of neural stem cells in the subventricular zone of n...

a prospective study of 550 consecutive mothers delivered in amin ob. gyn center of isfahan university was performed to determine the relationships between maternal anemia, placental weight and neonatal birth weight. the important findings were marked placental hypertrophy in anemic mothers. (r= -/9.95) .it is probable that in anemic mothers placental hypertrophy is a compensatory mechanism resp...

OBJECTIVE The incidence of Transient Tachypnea of Newborn (TTN) is higher in infants born by cesarean section than with  vaginal delivery. Treatment of transient tachypnea of newborn is supportive. The purpose of this study was to assess the effect of restricted fluid volume intake on the course of respiratory distress in patients with TTN. METHODS This is a quasi-experimental clinical trial ...