background: hyperbilirubinemia is the single most common abnormal physical finding in the first week of life and is commonly managed by phototherapy with its inherent complications.  a lesser known complication of the phototherapy is hypocalcemia.   objective: to study the prevalence of phototherapy-induced hypocalcemia and to compare it between premature and full-term babies.   methods: this s...

kernicterus (bilirubin induced encephalopathy) is an uncommon disorder with tragic consequences, especially when it affects healthy term and near-term neonates. appointment of cut off value of total serum bilirubin level that have a safe margin for early prompt treatment, as a result, prevention of kernicterus. in our study, all of icteric neonates that admitted in our center in 1 year were enr...

INTRODUCTION In the search for biomarkers that allow the prediction of neonatal growth and development, placental growth hormone(PGH), pituitary growth hormone (GH1), insulin-like growth factor 1 (IGF-1), and ghrelin concentrations were assessed in the amniotic fluid and in the umbilical cord blood of 92 neonates. MATERIAL AND METHODS The proteins were assayed by the ELISA method. Their conce...

The main function of adipocyte fatty acid-binding protein (A-FABP) is to regulate fatty acid metabolism as its molecular chaperone. The clinical significance of A-FABP in hypoxic-ischemic brain damage (HIBD) neonates is not yet clear. Free fatty acid (FFA) in cerebral cortex increases along with hypoxia ischemia degree. Thus, we aimed to investigate whether FFA can induce A-FABP expression and ...

methods this prospective observational study was conducted in a tertiary level neonatal intensive care unit, princess esra hospital, deccan college of medical sciences, hyderabad, telangana, india. consecutive intramural and extramural neonates admitted to neonatal intensive care unit with the rh-negative mother’s blood group and hyperbilirubinemia were enrolled. neonates born to rh+ve mothers ...

During the first weeks of life, preterm neonates show fewer circadian rhythms in their physiological parameters than full-term neonates. To determine whether preterm neonates differ in their temporal adaptation to the day-night cycle from full-term neonates at the early age of 1 week, we compared activity-rest behavior of both groups. Activity-rest behavior of 10 neurologically healthy preterm ...

BACKGROUND In September 2005, Texas Children's Hospital initiated a protocol for all neonates presenting to the emergency department (ED) with hyperbilirubinemia based on the American Academy of Pediatrics guidelines. As part of the protocol, low-risk neonates with hyperbilirubinemia requiring phototherapy are treated in the ED observation unit (EDOU). OBJECTIVE The aim of the study was to co...

The aims of this study were to detect the frequency at which the different types of neonatal jaundice occur in Makkah and to estimate the malondialdehyde (MDA) levels. This study included 239 neonates with neonatal jaundice, 20 anemic neonates and 21 healthy neonates. ABO incompatibility was observed in 31.6% of neonates with indirect hyperbilirubinemia, in 14.3% of those with early onset jaund...

Objective: The aim of this study is to determine the characteristics radiological manifestations and risk factors in neonates with necrotizing enterocolitis (NEC). Methods: A prospective study over on year starting from January 2008, conducted on 55 neonates with suspected NEC admitted at Children Hospital, Cairo University. Serial X-ray for all neonates were done and assessed Results: 31 (56.4...

There is an incomplete understanding of the differences between neonatal immune responses that contribute to the increased susceptibility of neonates to some viral infections. We tested the hypothesis that neonates are more susceptible than adults to mouse adenovirus type 1 (MAV-1) respiratory infection and are impaired in the ability to generate a protective immune response against a second in...