Introduction: Optical coherence tomography is a technology that allows obtaining high resolution images of tissues in vivo, enabling the measurement of ocular structures, including the retinal nerve fiber layer and macular thickness. As a noninvasive test it’s particularly useful in children, but its applicability is limited by the existence of normative values for adults only. Purpose: To esta...

Early attrition of nerve fiber bundles in glaucoma causes slit-like gaps to appear among the normally uniform, striated arcuate bundles of the retinal nerve fiber layer. The nerve fiber layer thins progressively, and its vessels become exposed as the defects coalesce, deepen, and widen with advancing disease. These changes in the peripapillary retina are exemplified photographically and compare...

Postherpetic neuralgia (PHN) is a common and exceptionally drug-resistant neuropathic pain condition. In this cross-sectional skin biopsy study, seeking information on the responsible pathophysiological mechanisms we assessed how ophthalmic PHN affects sensory and autonomic skin innervation. We took 2-mm supraorbital punch skin biopsies from the affected and unaffected sides in 10 patients with...

purpose : this study was designed to assess and compare the thickness of the peripapillar retinal nerve fiber layer (rnfl) in amblyopic and normal eyes in unilateral strabismic ambelyopia using scanning laser polarimeter. methods : scanning laser polarimetry was performed on 17 patients with unilateral strabismic amblyopia who had an absence of neurologic diseases or glaucoma with a minimum age...

SUMMARY The use of in vivo confocal microscopy (IVCM) is rapidly emerging as an important clinical tool to evaluate changes in corneal sensory nerves as a surrogate measure for diabetic peripheral neuropathy. Commonly used metrics to document and grade the severity of diabetes and risk for diabetic peripheral neuropathy include nerve fiber length, density, branching and tortuosity. In addition ...

OBJECTIVE Corneal confocal microscopy (CCM) is a rapid, noninvasive, clinical examination technique that quantifies small nerve fiber pathology. We have used it to assess the neurological benefits of pancreas transplantation in type 1 diabetic patients. RESEARCH DESIGN AND METHODS In 20 patients with type 1 diabetes undergoing simultaneous pancreas and kidney transplantation (SPK) and 15 cont...

Peripheral nerve injuries (PNI) can lead to lifetime loss of function and disfigurement. Different methods such as conventional allograft procedures and using of biological tubes have problems for damaged peripheral nerves reconstruction. Designed scaffolds with natural and synthetic materials are now widely used in the reconstruction of damaged tissues. Utilization of absorbable and non-absorb...

Peripheral nerve injuries (PNI) can lead to lifetime loss of function and disfigurement. Different methods such as conventional allograft procedures and using of biological tubes have problems for damaged peripheral nerves reconstruction. Designed scaffolds with natural and synthetic materials are now widely used in the reconstruction of damaged tissues. Utilization of absorbable and non-absorb...

If such a nerve fiberwere to be directly joined to amuscle fiber of, say, 50μmin diameter, then as the propagating action potential reached the nerve–muscle junction, the local circuit current density set up in the muscle would be considerably reduced from that in the nerve. This reduction would occur because the nerve and muscle must have the same total current, a consequence of current conser...

normal 0 false false false en-us x-none ar-sa background: this study was designed to investigate the effect of vitiligo on the retinal nerve fiber layer (rnfl) thickness. materials and methods: this prospective study was conducted in the department of ophthalmology at kä±rä±kkale university during 2010 and 2011.sixty eight eyes of 34 vitiligo patients were included in the study. eighty four eye...