Optic disc drusen (ODD) are benign congenital anomalies of the optic nerve characterized by calcified hyaline bodies. While superficial drusen can be diagnosed easily during fundus examination, detecting buried drusen requires the use of additional imaging methods such as B-scan ultrasonography (USG), fundus fluorescein angiography (FFA), computed tomography (CT) and fundus autofluorescence (FA...

PURPOSE To report a new familial case of the recently described autosomal recessive syndrome of nanophthalmos-retinitis pigmentosa-foveoschisis-optic disc drusen, which arises from compound heterozygosity for Membrane Frizzled-Related Protein (MFRP) mutations in a sibling pair of Mexican origin. METHODS Ophthalmological assessment included slit-lamp and dilated fundus examination, applanation...

PURPOSE Late-onset central areolar choroidal dystrophy (CACD) may easily be confused with geographic atrophy (GA) in AMD. To detect discerning features, the morphologic changes in CACD patients and in AMD patients were assessed with confocal scanning laser ophthalmoscopy (cSLO), fundus autofluorescence (FAF), and spectral-domain optical coherence tomography (SD-OCT). METHODS A total of 30 CAC...

GİRİŞ VE AMAÇ: Yaşa bağlı makula dejenerasyonu (YBMD) olan hastalarda ultra geniş açılı renkli fundus fotoğrafları ve otofloresans (FOF) görüntülerini değerlendirmek periferik retina değişikliklerini belirlemek.
 YÖNTEM: Bu çalışmaya YBMD’li 58 hastanın 116 gözü, kontrol grubu olarak da sağlıklı 30 60 gözü dahil edildi. Standart bir görüntüleme protokolü kullanılarak Optos 200Tx cihazı ile...

Artificial intelligence (AI) represents a growing and promising branch of computer science that is expanding the horizon prediction, screening, disease monitoring. The use multimodal imaging in retinal diseases particularly advantageous to valorize integration machine learning deep for early diagnosis, management disorders. In age-related macular degeneration (AMD) beyond its diagnosis characte...

Abbreviations Introduction 1. Functional aspects of drusen regression in AMD 1.1. Etiology and pathogenesis of AMD 1.2. Clinical manifestations of AMD 1.3. Drusen 1.4. Functional characteristics of the retina in aging and AMD 1.5. Fundus autofluorescence 1.6. Fundus autofluorescence imaging and its limitations 1.7. Fundus autofluorescence anomalies associated with AMD 1.8. Functional correlates...

Computerized image processing was used to analyze color fundus photographs of 11 patients (22 eyes) with macular drusen who were followed for more than 2 years (mean follow-up, 4.7 years). Significant changes over time (more than +/- 20% of baseline area) were measured in the surface area of macular drusen in 18 of 22 (82%) eyes. An increase in the drusen area was associated significantly with ...

OBJECTIVE To determine differences in the prevalence of age-related macular degeneration (AMD) and its fundus manifestations in a population-based sample of older black and white Americans. DESIGN Cross-sectional population-based study of 2520 participants of whom 1854 are white and 666 are black. Mean age was 73.5 years. Stereoscopic color fundus photographs were graded for presence, severit...

INTRODUCTION Examination of the ocular fundus is a fundamental component of the general physical examination and critical to the diagnosis of lifeand sight-threatening medical conditions among patients with certain presenting complaints, such as headache. In addition, populationbased studies have shown the prognostic value of retinal microvascular findings in cardiovascular and neurologic disea...

PURPOSE To image and quantify the spatial distribution of fundus autofluorescence in normal subjects, to determine its age dependence, and to document the deviation from normal in patients with age-related macular disease. METHODS Using a confocal laser scanning ophthalmoscope (cLSO), the intensity and spatial distribution of fundus autofluorescence was studied in 33 normal subjects, 97 eyes ...