AIM The aim of this study was to investigate the effects of metamizole sodium on neural tube development in the early stage chick embryo model that complies with the first month of embryonic development in mammals. MATERIAL AND METHODS A total of 40 fertilized chicken eggs were divided into 4 equal groups. The eggs were incubated in the incubator at a temperature of 37.8±2°C with 60±5% humidi...

Fraternities that include a fetus or person with a neural tube defect are remarkable for a high rate of recurrence of this type of malformation, about seven to eight times the overall rate (Record and McKeown, 1950; MacMahon, Pugh, and Ingalls, 1953; Carter, David, and Laurence,1968) and a higher than average rate of abortions (Murphy, 1940; Record and McKeown, 1950). Murphy (1940) found that a...

An oil tube defect detection method based on self-adaptive genetic fuzzy neural network is proposed, and it got the original information by multi-group vortex sensors and leakage magnetic sensors. We made multi-scale wavelet transform and frequency analysis to multi-channels original data and extracted multiattribute parameters from time domain and frequency domain, and then we selected the key...

Evidence is presented to support the recent suggestion that human neural tube closure is similar to that observed in mice, and comprises several regionally distinct closure sites rather than being a simple zipping up process. Seven subjects, each with more than one neural tube defect (NTD), are described. Comparative studies of the location of the lesions in relation to the closed parts of the ...

The recurrence of isolated neural tube defects in a population of women from a genetic counselling clinic was found to be 3.4%. After one baby with a neural tube defect the recurrence was 2.3%. Of the 15 pregnancies of women who had two previous babies with neural tube defects, there were three further recurrences. These findings show that the Hungarian recurrence risk of isolated neural tube d...

BACKGROUND In the absence of clinical folate deficiency, periconceptional supplementation with folic acid reduces a woman's risk of having an infant with a neural-tube defect. Since antiserum to folate receptors induces embryo resorption and malformations in rats, we hypothesized that autoantibodies against folate receptors in women may be associated with pregnancy complicated by a neural-tube ...

BACKGROUND A previous report described the presence of autoantibodies against folate receptors in 75% of serum samples from women with a history of pregnancy complicated by a neural-tube defect, as compared with 10% of controls. We sought to confirm this finding in an Irish population, which traditionally has had a high prevalence of neural-tube defects. METHODS We performed two studies. Stud...

endotracheal tube (ett) cuff herniation is a rare, and often difficult to diagnose, cause of bronchial obstruction. we present a case of outside cuff herniation of an endotracheal tube that caused pulmonary right lung atelectasis. a 29-year-old man ,a case of car accident with multiple fractures, was admitted to the emergency ward and transferred to the operating room(or) for open reduction and...

Neural tube defects including spina bifida are common and severe congenital disorders. In mice, mutations in more than 200 genes can result in neural tube defects. We hypothesized that this large gene set might include genes whose homologs contribute to morphogenesis in diverse animals. To test this hypothesis, we screened a set of Caenorhabditis elegans homologs for roles in gastrulation, a to...

OBJECTIVES To evaluate the prevalence and factors associated to neural tube defects in liveborn and stillborn infants delivered at the Hospital das Clínicas, UFMG, from January 8, 1999 to July 31, 2000. METHODS This is a descriptive study, based on a database, according to the Latin-American Collaborative Study of Congenital Malformation (ECLAMC) rules. Reports on liveborn and stillborn infan...