BACKGROUND Sorbin, a 153 amino acid peptide isolated from porcine intestine, was localised by immunohistochemistry in endocrine cells of the intestinal mucosa and pancreas and in the enteric nervous system in the pig. AIMS To identify sorbin cells in normal human digestive tissues and to explore the expression of sorbin in 37 digestive endocrine tumours: 14 intestinal carcinoid tumours and 23...

Background—Sorbin, a 153 amino acid peptide isolated from porcine intestine, was localised by immunohistochemistry in endocrine cells of the intestinal mucosa and pancreas and in the enteric nervous system in the pig. Aims—To identify sorbin cells in normal human digestive tissues and to explore the expression of sorbin in 37 digestive endocrine tumours: 14 intestinal carcinoid tumours and 23 e...

Intelligent systems for the diagnosis and classification of Endocrine Myopathy (EM) plays very significant role in the medical field. Neuro-fuzzy system is refers to combinations of artificial neural networks and fuzzy logic, in which fuzzy system works like human reasoning and the learning structure of neural networks. The plan of this paper is to present the Neuro-fuzzy system for the classif...

Originating from cells of the diffuse endocrine system the endocrine tumours of the gut and the pancreatic tract are rare entities characterized by a common phenotypic aspect and producing several bioactive substances including growth factors. Two major categories are identified: well-differentiated and poorly differentiated tumours. The clinical behaviour varies ranging from benign to low grad...

Background. Earlier we showed, by constructing regression models, that plasma nitrogenous metabolites (uric acid, urea, creatinine and bilirubin) are able to influence the state of trait anxiety, autonomic central nervous endocrine systems. In this study same cohort, other methodological approaches were used. Materials Methods. The object observation almost healthy volunteers: 30 females (30÷76...

Introduction Breast cancer is a complex disease which constitutes the leading cause of in women globally. Conventional treatment modalities include surgery, chemotherapy, radiation therapy, and hormonal therapy; all have their limitations often result significant side effects or toxicity. Targeted radionuclide therapy based on theranostic approach, has been successfully applied several malignan...