A small-cell carcinoma is one of the histologic subtypes of primary neuroendocrine carcinomas of the breast. A small-cell carcinoma is a rare entity of the breast and exhibits similar morphologic features as neuroendocrine tumors of the gastrointestinal tract and lung. We present the imaging and pathologic findings of a primary small-cell neuroendocrine carcinoma of the breast. This is the firs...

Background: Certain marker studies have practical importance in the biology of prostate cancer. The purpose of this study was to determine whether the quantification of certain neuroendocrine and proliferative markers obtained during transurethral resection or prostatectomy, would help in the prognostic evaluation of prostatic adenocarcinomas. Methods: The present study was performed on samples...

Primary small cell neuroendocrine tumour of the breast is very rare with less than 30 cases have been reported in the literature so for. The morphological and immunohistochemical patterns of this tumour are similar to small cell neuroendocrine cancer of the lung. For this reason, it is often difficult to distinguish a primary small cell neuroendocrine cancer of the breast from a metastatic lesi...

BACKGROUND Neuroendocrine carcinoma is rare with a proportion of less than 2% in gallbladder malignancies, cases of gallbladder neuroendocrine cell carcinoma coexisting with adenocarcinoma are exceptionally rare, and the prognosis is dismal. METHODS Herein, we presented an unusual case of poorly differentiated gallbladder neuroendocrine cell carcinoma coexisting with poorly differentiated ade...

Gastric Neuroendocrine Tumors (NET)s are classified on the basis of criteria that are common to all gastrointestinal and pancreatic neuroendocrine neoplasms. Most neuroendocrine neoplasms of the stomach are NETs –well differentiated, nonfunctioning enterochromaffin–like(ECL) cell carcinoids (ECL cell NETs)-arise predominantly in the corpus-fundus region [1]. Three distinct types are recognized :

abstract primary neuroendocrine carcinoma of the breast is a very rare malignant tumor. there are not many cases reported in the english literature since it was first documented in 1983. reports on the imaging features, in particular the ultrasonographic features of this rare tumor are scarce. herein, we report a case of aggressive primary infiltrating neuroendocrine carcinoma of the breast, ma...

Small-cell lung cancer and other aggressive neuroendocrine cancers are often associated with early dissemination and frequent metastases. We demonstrate that neurogenic differentiation 1 (NeuroD1) is a regulatory hub securing cross talk among survival and migratory-inducing signaling pathways in neuroendocrine lung carcinomas. We find that NeuroD1 promotes tumor cell survival and metastasis in ...

Transient pulmonary neuroendocrine cell hyperplasia and non-neuroendocrine lung tumors develop in nitrosaminetreated hamsters, which we hypothesized might modulate epithelial cell phenotype by expressing gene(s) homologous to human chromosome 3p gene(s) deleted in small cell carcinoma of the lung (SCLC). We differentially screened a chromosome 3 library using nitrosamine-treated versus normal h...

neuroendocrine tumors are most often located in the intestine and lungs but they can arise from other areas of the body. limited data is available on epidemiology and clinical patterns of neuroendocrine tumors in iran. we analyzed medical records of 34 patients from 2 cancer centers (emam khomeini hospital and omid charity cancer center) in west azarbaijan province of iran with neuroendocrine t...

mucinous carcinoma of the breast is a well-differentiated type of adenocarcinoma accounting for 2-5% of all breast cancers. pure mucinous carcinoma of the breast has a favorable prognosis, usually seen in post-menopausal women. neuroendocrine differentiation has been described in both in-situ and infiltrating breast cancers .mucinous carcinomas of the breast appear to have the greatest associat...