The treatment of supratentorial malignant gliomas has continued to be a major problem for neurosurgeons and oncologists. Post-operative conventional radiotherapy is known to prolong survival and to enhance the quality of life. Local persistence of tumor kills the majority of patients. Fast neutron irradiation is being utilized to treat malignant gliomas based on its reputed radiobiological adva...

Prediction of neutron flux at the irradiation devices of a research reactor facility is essential for the design and evaluation of experiments involving material irradiations. A computational model of the Greek Research Reactor (GRR-1) was developed using the Monte Carlo code MCNP with continuous energy neutron cross-section data evaluations from ENDF/B-VI library. The model included detailed g...

Poly(L-lactic acid) microspheres loaded with holmium-166 acetylacetonate (166Ho-PLLA-MS) are a novel microdevice for intra-arterial radio-embolization in patients with unresectable liver malignancies. The neutron activation in a nuclear reactor, in particular the gamma heating, damages the 166Ho-PLLA-MS. The degree of damage is dependent on the irradiation characteristics and irradiation time i...

Neutron activation cross sections for Bi and Co at 386 MeV were measured by activation method. A quasi-monoenergetic neutron beam was produced using the (7)Li(p,n) reaction. The energy spectrum of these neutrons has a high-energy peak (386 MeV) and a low-energy tail. Two neutron beams, 0° and 25° from the proton beam axis, were used for sample irradiation, enabling a correction for the contribu...

Background: Boron neutron capture therapy (BNCT) is a radiotherapy that combines biological targeting and high linear energy transfer. A potential therapeutic approach for non-small cell lung cancer (NSCLC) is considered. However, dose in lung tumor is not homogeneous, and it will reduce the effect of BNCT treatment. In order to improve the dose distribution of BNCT, the multi-field irradiation...

Irradiation effects in graphite were one major research area in the past, partially due to its application as a moderator in thermal nuclear reactors. Graphite is still a material of choice for nuclear applications due to its low cross-section for neutron absorption. The influence of irradiation damage produced by different kinds of ions on several properties of graphite was reviewed by Kelly (...

The Avalanche Photodiodes (APD) were chosen as photon sensors for the barrel region of the CMS electromagnetic calorimeter. The LHC will be a hard environment for what concerns the radiation levels in the detectors. The most relevant damage on APDs is caused by neutrons that produce an increase in the dark current of these devices. In the CMS-ECAL collaboration a big effort was indeed done to u...

introduction bnct is an effective method to destroy brain tumoral cells while sparing the healthy tissues. the recommended flux for epithermal neutrons is 109 n/cm2s, which has the most effectiveness on deep-seated tumors. in this paper, it is indicated that using d-t neutron source and optimizing of beam shaping assembly (bsa) leads to treating brain tumors in a reasonable time where all iaea ...

The problem of irradiation-assisted stress corrosion cracking (L4SCC) in reactor cores is currently being addressed using different types of particle irradiation (electrons, heavy and light ions) to study the effect of neutron damage. Differences among the types of irradiation include particle type, temperature, dose and dose rate. In using different types of particle irradiation, the issue bec...

The 250kW TRIGA Mark II research reactor, Vienna, is equipped with experimental facilities inside and outside the reactor core. Outside the core, there are four beam tubes (three radial and one tangential beam tube), a thermal column and a neutron radiography collimator, supplying neutrons for irradiation experiments. These experiments include neutron radiography, neutron tomography, neutron ac...