During the last two decades, there has been a revolution in the understanding of hepatic pathophysiology and in the treatment of liver disease. There is not time to review all of the new developments. Instead, I will touch briefly on two areas which are still evolving and in which I have worked. The first topic will concern portal physiology.

The human brain is the most complex structure known to man. The complexity of the brain can compete with that of the universe. Neuroscience, the study of the brain and other parts of the nervous system, developed first slowly and then at a rapid pace. Similar to research in many other areas, research in neuroscience is driven by people’s curiosity and ingenuity. The brain is a giant information...

In pattern recognition, learning, and data mining one obtains information from information-carrying objects. This involves an objective definition of the information in a single object, the information to go from one object to another object in a pair of objects, the information to go from one object to any other object in a multiple of objects, and the shared information between objects. This ...

volume 123 | number 4 | April 2015 • Environmental Health Perspectives As many of you may recall, Hugh A. Tilson retired as Editor-in-Chief of EHP in August 2014. Historically, the Editor-in-Chief of EHP had two major functions: providing scientific and strategic vision, and managing day-to-day office operations. This dual role derived from EHP ’s unique position as a government publication sta...