Mesogenic vaccine strains of Newcastle disease virus (NDV) are widely used in many countries of Asia and Africa to control the Newcastle disease of poultry. In India, the mesogenic strain R2B was introduced in 1945; it protects adult chickens that have been preimmunized with a lentogenic vaccine virus and provides long-lasting immunity. In this article, we report the complete genome sequence of...

We report the complete genomic sequence of a novel Newcastle disease virus (NDV) strain, duck/China/Guangxi19/2011, isolated from a white duck in Guangxi Province, southern China. Phylogenetic analysis based on a fusion gene comparison with different NDV strains revealed that duck/China/Guangxi19/2011 is phylogenetically close to genotype IX NDV, and the deduced amino acid sequence of the fusio...

The phosphoprotein, or P protein, of Newcastle disease virus is required for transcription of the viral genome (1) and is the major product of the P gene (2). The cDNA for the complete P gene of Newcastle disease virus (strain Beaudette C) was cloned and sequenced in both directions by using Bal-3 1 and restriction endonuclease subcloning. The largest open reading frame of the P gene codes for ...

Underwood and co-workers (27) recently re ported that a number of a-ketoaldehydes and closely related compounds were active against Newcastle disease virus (NJKD strain) and in fluenza virus (PR-8 strain) in embryonated eggs. These substances also had potent virus-inactivat ing effects in vitro. Underwood and Weed (28) found that glyoxal and methylglyoxal were active virucides in blood. Consequ...

newcastle disease (nd) is one of the most serious illnesses of chickens. live vaccines are widely used to prevent chicken from the disease all over the world. to access the effective and potentiate nd vaccine, a homogenous subpopulation from lasota strain was selected following cultivation of the virus on primary chicken embryofibroblast (cef) cells. pathogenicity indices and molecular characte...

objectives the current research aimed to study achillea millefolium and thymus vulgaris antiviral activity against newcastle disease virus (ndv). materials and methods the antiviral activity of the plants was measured by the reduction assay of viral titer, and explained by inhibition percentage (ip). background nowadays natural products such as pure compounds and plant extract scan provide unli...

background and aims: ndv (newcastle disease virus) is one of the viruses that cause disease in avian with severe economic losses in the poultry industry in many countries. fusion protein (f) which plays a major role in the virus pathogenicity contains several regions that have a role in the fusion process. mutation in the sequence of hr1 & hr2 regions of this protein prevents fusion of the viru...

In an effort to improve current technology for detection of Newcastle disease virus in convalescent birds, a procedure has been developed for efficient reactivation of virus that has been neutralized by antibody. The reactivation capabilities of fluorocarbon treatment, ultrasonic treatment, pH extremes, and proteolytic digestion were evaluated using the LaSota strain of virus. Reactivation was ...

Background and Aims: Newcastle disease virus (NDV) is one of the major pathogen in poultry. Vaccination is intended to control the disease as an effective solution nevertheless this virus is a growing threat to the poultry industry. F gene open reading frame (ORF) from NDV is 1650 bp, encoding a protein of 553 amino acids that can induce protective immunity alone. The F glycoprotein on the surf...