BACKGROUND Nigella sativa Linn (Ranunculaceae) is popularly known as black cumin with a wide spectrum of pharmacological activities including anti-inflammatory, antibacterial, antifungal and antihelmenthic. The seeds are externally applied for eruptions of skin. The seeds are used traditionally for psoriasis tropicus with general pain and eruption of patches. OBJECTIVE The ethanolic extract o...

The aim of this study was to determine the feasibility of producing Nigella sativa powder under a foam mat drying technique. A central, composite design of experiments was used to optimize the drying condition and compare the solubility, the antioxidant and mineral content of roasted Nigella sativa, and the foam mat dried Nigella sativa powder. Foams were prepared from Nigella sativa solution b...

infection with helicobacter pyloriis the most common cause of stomach and duodenal ulcers. about more than 80 % of people are infected with h. pylori in developing countries. h. pyloriuses urease enzyme product “ammonia” in order to neutralize and protect itself from the stomach acidic condition and urease enzyme activity has been shown to be essential to the colonization of h. pylori. inhibito...

We investigated the toxicity of the fixed oil of Nigella sativa L seeds in mice and rats through determination of LD50 values and examination of possible biochemical, hematological and histopathological changes. The acute toxicity of Nigella sativa fixed oil was investigated in mice. LD50 values, obtained by single doses, orally and intraperitoneally administered in mice, were 28.8 ml/kg body w...

Abstract Background This review of relevant medicinal plants is based on the fundamental knowledge accumulated by indigenous people Ethiopia and to identify which types selected for phytochemical analysis were analyzed one not at Ethiopian levels. In this review, most traditional plant species found used in are chosen. Results The qualitative analysis, some important phytochemicals such as phen...

application of most antibiotic growth promoters as feed additives has been banned in a lot of countries due to cross-resistance against pathogens and residues in tissues. therefore, scientists are searching for alternatives to antibiotics nowadays. medicinal plant extracts are one of the alternatives that have anti-microbial and growth promoting effect on poultry. in this paper, the benefits of...

Aim: To identify the anti-mutagenic effect of Nigella sativa on the experimentally induced chronic diabetes (type – II) in Wistar rats. Materials and Methods: The anti-mutagenic effect was evaluated in Nigella sativa treated diabetic rats against the streptozotocin nicotinamide (STZ-NA) (at a dose rate of 45-110 i.p mg/kg b.wt for 90 days) induced type-II diabetes mellitus using bone marrow mic...