Near infrared (NIR) multiphoton microscopy is becoming a novel optical tool of choice for fluorescence imaging with high spatial and temporal resolution, diagnostics, photochemistry and nanoprocessing within living cells and tissues. Three-dimensional fluorescence imaging based on non-resonant two-photon or three-photon fluorophor excitation requires light intensities in the range of MW cm(-2) ...

A novel sandwich nanomedicine (GO-BNN6) for near-infrared (NIR) light responsive release of nitric oxide (NO) has been constructed by self-assembly of graphene oxide (GO) nanosheets and a NO donor BNN6 through the π-π stacking interaction. The GO-BNN6 nanomedicine has an extraordinarily high drug loading capacity (1.2 mg BNN6 per mg GO), good thermal stability, and high NIR responsiveness. The ...

Triple-doped (Yb(3+)/Er(3+)/Tm(3+)) KMnF3 nanocubes with uniform sizes of 250 nm were synthesized by a facile hydrothermal route using the oleic acid as the capping agent. It was found that these nanocubes can simultaneously exhibited four-color (blue, green, red and NIR) upconversion emissions under a single 980 nm near-infrared (NIR) laser excitation, which should have potential multicolor in...

PURPOSE Nanoparticle (NP)-enabled near infrared (NIR) photothermal therapy has realized limited success in in vivo studies as a potential localized cancer therapy. This is primarily due to a lack of successful methods that can prevent NP uptake by the reticuloendothelial system, especially the liver and kidney, and deliver sufficient quantities of intravenously injected NPs to the tumor site. H...

Introduction: Photothermal therapy (PTT) is a nanotechnology-assisted cancer hyperthermia approach in which the interaction between laser light and plasmonic nanoparticles generates a localized heating for thermoablation of the tumor. Recent efforts in the area of PTT follow two important aims: (i) exploitation of targeting strategies for preferential accumulation of plasmonic ...

Cyrille Boyer, May Lim, and co-workers highlight recent advances in upconversion nanoparticles (UCNPs) as NIR-initiated controlled drug delivery systems. Surface modification strategies are reviewed alongside with the influence of the laser power intensity and illumination time on the drug release pattern in article 1500437. NIRto-UV/visible UCNPs have emerged as potential remotecontrolled nano...

Elevating the reaction temperature is an effective method to accelerate protein enzymatic digestion because it can promote protein denaturation and enzyme activities. In this study, we demonstrated a new photothermal heating method to assist protein tryptic digestion on glass slides. A glass slide coated with layer-by-layer gold nanoparticles (Glass@AuNPs), combined with the use of a near infra...

Near-infrared photoimmunotherapy (NIR-PIT) is a newly-established cancer treatment which employs the combination of an antibody-photoabsorber conjugate (APC) and NIR light. When NIR light is absorbed by APC-bound tissues, a certain amount of heat is generated locally. For the most part this results in a subclinical rise in skin temperature, however, excessive light exposure may cause non-specif...

The application of surface plasmon resonance (SPR) measurements to the study of ultrathin organic and inorganic films adsorbed onto gold surfaces utilizing nearinfrared (NIR) excitation from 800 to 1152 nm is described. SPR scanning angle measurements of film thickness are demonstrated at 814 and 1152 nm using lowpower diode and HeNe laser sources, respectively. Several advantages of SPR in the...

The near infrared (NIR) absorption and average particle size of gold nanostars (GNSs) can be precisely controlled by varying the molar ratios of cucurbit[7]urils (CB[7]) and GNSs in aqueous solution. GNSs modified with CB[7] achieved high cargo loading with thermally activated release upon the NIR laser irradiation.