Purpose. To describe a case of postoperative scleritis caused by a novel strain of Nocardia resistant to linezolid and trimethoprim-sulfamethoxazole (TMP-SMX). Methods. Case report of a patient with microbiologically proven scleritis due to Nocardia asteroides. Results. The patient presented with pain, redness, and nodules on the sclera three months following pterygium excision with mitomycin C...

Infections with Nocardia species are generally seen in immunocompromised subjects. In this report, we present a case of pleuropulmonary and skin Nocardia cyriacigeorgici infection in a male patient with Behcet's disease who used corticosteroids and immunosupressives for a long period of time. He died before the diagnosis of Nocardia infection was made.

The producer of SO-075R1,a newanthracycline group antibiotic was identified as Nocardia brasiliensis. SO-075R1 was active against Gram-positive bacteria, but not active against Gram-negative bacteria or fungi. All tested Nocardia brasiliensis strains as well as the producer itself were resistant to SO-075R1, although four other pathogenic Nocardia, i.e. N. asteroides, N. nova, N. farcinica and ...

Nocardia farcinica is a gram-positive, partially acid-fast, methenamine silver-positive aerobic actinomycete that is infrequently associated with nocardiosis. The relative frequency of Nocardia farcinica isolates in nocardiosis is unknown but thought to be under diagnosis. It is increasingly been recognized in immunocompetent patients. We report a case of disseminated Nocardia farcinica causing...

RATIONALE Nocardia species are aerobic saprophytic bacilli. Among Nocardia species, Nocardia otitidiscaviarum (N otitidiscaviarum) is rarely reported in pulmonary infection. PATIENT CONCERNS We reported a case of N otitidiscaviarum pneumonia in a cotton farmer. DIAGNOSES N otitidiscaviarum pneumonia was identified by mass spectroscopy. INTERVENTIONS Combined treatments (amikacin, imipenem...

Nocardiosis is a rare infectious disease due to Nocardia infections. In this report, we present a rare case of cutaneous nocardiosis with involvement of the trachea, anterior mediastinum and sternum. The strain of Nocardia has been isolated from bacterial culture of infected tissue. 16s rRNA sequencing confirmed that it contained the Nocardia genus. The patient was successfully treated with Co-...

2 different strains of Nocardia were isolated from a lung mass in a post kidney-pancreas transplant patient through convex endobronchial ultrasound transbronchial needle aspiration (EBUS-TNBA). TBNA cultures (16S rRNA gene-targeted PCR sequencing) subsequently grew Nocardia beijingensis and Nocardia arthritidis.

Nocardia identification required laborious and time-consuming phenotypic and chemotaxonomic methods until molecular methods were developed in the mid-1990s. Here we reassessed the capacity of PCR-restriction enzyme pattern analysis (PRA) of the hsp65 gene to differentiate Nocardia species, including 36 new species. Our results confirm that hsp65 PRA must no longer be used for Nocardia species i...

Nocardia farcinica is one of the more recently identified species of the Nocardia genus. Nocardia farcinica keratitis is a rare occurrence, with only eight previously reported cases. Semi-permeable rigid contact lens use was associated with one of these reported cases. We report the first case of an extended wear soft contact lens-related Nocardia farcinica keratitis and recommend a new treatme...