Taking account of increasing world population life expectancy, health services will face with a large number of elderly people with chronic age-related diseases. It has been established that chronic diseases are usually accompanied by oxidative stress induced by the overproduction of reactive oxygen species damaging cellular constituents, under conditions of weakening antioxidant defense system...

Methanol is primarily metabolized by oxidation to formaldehyde and then to formate. These processes are accompanied by formation of superoxide anion and hydrogen peroxide. This paper reports data on the effect of methanol on antioxidant status and lipid peroxidation in lymphoid organs such as the spleen, thymus, lymph nodes and bone marrow of rats. Male Wistar albino rats were intoxicated with ...

The cells continuously produce free radicals and reactive oxygen species as a part of metabolic processes. Increased aerobic metabolism during exercise is a potential source of oxidative stress. Also, anaerobic physical activity and oxidative stress are interrelated because the intense anaerobic activity leads to damage proteins, lipids and nucleic acids in muscle cells and blood. Complex syste...

Male albino rats of Wistar strain were injected intraperitoneally with nicotine or/and resveratrol for 4 weeks. Serum Interleukin-2, Interleukin-6, alpha-fetoprotein and tumor necrosis-alpha, as well as plasma 8-hydroxydeoxyguanosine of nicotine-treated rats were increased significantly. Myeloperoxidase, xanthine oxidase, nitric oxide, lipid peroxidation and total oxidative status of the lung i...

Under normal conditions, the physiologically important intracellular levels of reactive oxygen species (ROS) are maintained at low levels by various antioxidant systems in the body but at high concentrations, they produce adverse modifications to cell components such as lipids, proteins and DNA. In humans, oxidative stress is involved in the development of cancer, parkinson's disease, alzheimer...

This short review briefly introduces the formation of reactive oxygen species (ROS) as by-products of oxidation/reduction (redox) reactions, and the ways in which the antioxidant defense machinery is involved directly or indirectly in ROS scavenging. Major antioxidants, both enzymatic and non enzymatic, that protect higher plant cells from oxidative stress damage are described. Biochemical and ...

We examined whether non-enzymatic antioxidant defense systems are disrupted in the brain of rats with water-immersion restraint stress. When rats were exposed to water-immersion restraint stress for 1.5, 3 or 6 h, the brain had decreased ascorbic acid and reduced glutathione contents and increased lipid peroxide and nitric oxide metabolites contents at 3 h and showed further changes in these co...

Purpose of the study. To analyse free radical oxidation and antioxidant defense in patients diagnosed with early cervical cancer (CC) before after surgical treatment. Patients methods. Levels diene conjugates, malondialdehyde (MDA), superoxide dismutase (SOD), catalase, glutathione, glutathione- dependent enzymes, vitamins A E were determined 74 women under age 45 (48 those who at stage treatme...

boron (b) is a non-metal micronutrient which is essential for plants growth and development. formation of boron complex with cell wall matrix and phenolic compounds is a definite influence of boron in physiological process. it has been suggested that b-toxicity and deficiency may induce excess production of reactive oxygen species thereby promote defense responses by antioxidant enzymes or non-...

Plants are exposed to different ecological stress during their life cycle, and because of these tensions, free radicals shaped. Reactive oxygen species(ROS) have a fundamental ability support typical plant improvement tolerance. The disruption the proportionality ROS generation antioxidant defense systems is one primary effects biotic abiotic stress, resulting in an excess buildup oxidative dam...