نتایج جستجو برای: non insulin dependent diabetes

تعداد نتایج: 2177216  

Journal: :BMJ 1993
E Tuomilehto-Wolf J Tuomilehto G A Hitman A Nissinen J Stengård J Pekkanen P Kivinen E Kaarsalo M J Karvonen

OBJECTIVES To test the hypothesis that the genetic susceptibility to non-insulin dependent diabetes mellitus is the same as that to insulin dependent disease and to see whether glucose intolerance is associated with specific HLA haplotypes. DESIGN Population based study of men in 1989 first tested for glucose tolerance in 1984. HLA haplotypes, including HLA-A, C, B, DR, and DQ, were defined s...

Journal: :مجله دانشگاه علوم پزشکی کرمانشاه 0
golbarg ghiasi 1. student research committee, kermanshah university of medical sciences, kermanshah. 2. pharmacoeconomy and pharmaceutical management, faculty of pharmacy, tehran university of medical sciences, tehran amir farshchi 1. student research committee, kermanshah university of medical sciences, kermanshah. 2. pharmacoeconomy and pharmaceutical management, faculty of pharmacy, tehran university of medical sciences, tehran ali pourmotabbed dept. of phisiology, school of medicine, kermanshah university of medical sciences, kermanshah gholam-reza bahrami dept. of pharmacology, school of pharmacy, kermanshah university of medical sciences, kermanshah sayyed-ershad nedaee dept. of phisiology, school of medicine, kermanshah university of medical sciences, kermanshah

background: diabetes mellitus is one of the most important diseases in all over the world. insulin and its receptor are found in specific area of cns with a variety of regions-specific functions different from its role in direct glucose regulation in the periphery. the hippocampus and cerebral cortex distributed insulin and insulin receptor has been shown to be involved in brain cognitive funct...

Journal: :The American Journal of Clinical Nutrition 1996

Journal: :Diabetes 2004
Franck Mauvais-Jarvis Eugène Sobngwi Raphaël Porcher Jean-Pierre Riveline Jean-Philippe Kevorkian Christian Vaisse Guillaume Charpentier Pierre-Jean Guillausseau Patrick Vexiau Jean-François Gautier

Nonautoimmune ketosis-prone diabetic syndromes are increasingly frequent in nonwhite populations. We have characterized a cohort of patients of sub-Saharan African origin who had ketosis-prone type 2 diabetes (n = 111), type 1 diabetes (n = 21), and type 2 diabetes (n = 88) and were admitted to a hospital for management of uncontrolled diabetes. We compared epidemiological, clinical, and metabo...

Journal: :avicenna journal of medical biochemistry 0
hossein piri cellular and molecular research center, qazvin university of medical sciences, qazvin, ir iran; department of biochemistry and genetics, school of medicine, qazvin university of medical sciences, qazvin, ir iran bahram kazemi cellular and molecular biology research center, shahid beheshti university of medical sciences, tehran, ir iran; department of biotechnology, school of medicine, shahid beheshti university of medical sciences, tehran, ir iran iraj khodadadi department of biochemistry and nutrition, school of medicine, hamadan university of medical sciences, hamadan, ir iran maryam javadi department of nutrition and dietary therapy, school of medicine, qazvin university of medical sciences, qazvin, ir iran mojgan bandehpour cellular and molecular biology research center, shahid beheshti university of medical sciences, tehran, ir iran; department of biotechnology, school of medicine, shahid beheshti university of medical sciences, tehran, ir iran jamshid karimi department of biochemistry and nutrition, school of medicine, hamadan university of medical sciences, hamadan, ir iran

results this study shows the prepared gene construct is inducible by glucose. gene expression of preproinsulin was observed in muscle tissue of rabbits. conclusions these finding indicated that research in diabetes mellitus gene therapy could be performed on larger animals. objectives the purpose of this study was to construct glucose inducible insulin gene plasmid and use it in the muscle tiss...

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