INTRODUCTION Gastro-intestinal stromal tumours are the most common mesenchymal tumours of the gastro-intestinal tract. This case report highlights the necessity of early surgical intervention in such cases to avoid mortality due to rebleeding and to raise the awareness of rare causes of upper gastrointestinal bleed and their management. CASE PRESENTATION A 61-year-old male presented to the ac...

Common causes for obscure overt gastrointestinal bleeding originating from the small bowel include small bowel angioectasias, Crohn’s disease, ulcers and tumors. In tropical countries, intestinal ulcerations secondary to tuberculosis and parasitic infestations have also been described as causes of gastrointestinal bleeding. We present a very unusual case of massive obscure overt gastrointestina...

BACKGROUND Small intestinal lipomas are rare, usually asymptomatic, and most commonly encountered incidentally during investigation of the gastrointestinal tract for another reason. However, they may cause obscure gastrointestinal bleeding. CASE PRESENTATION We report a case of obscure gastrointestinal bleeding due to a small intestinal lipoma. A 69-year-old Japanese man on antiplatelet thera...

GASTRO-INTESTINAL STROMAL-TUMOURs (GASTRO-INTESTINAL STROMAL-TUMOURs) are tumours of the gut found mostly in stomach and small intestine. The complications Gastrointestinal (GI) bleeding, obstruction, pain rarely perforation. We reporting an abnormal presentation STROMAL-TUMOURS presenting as acute abdomen with Right Iliac Fossa (RIF) mass 57-year-old male. Contrast Enhanced Computed Tomography...

Imatinib mesylate is a widely used tyrosine-kinase inhibitor (TKI) in chronic myeloid leukemia (CML) treatment. Imatinib has contributed to complete and prolong cytogenetic responses so that it is now the standard treatment of CML. Recently, Imatinib mesylate has shown a significantly prolonged progression-free survival and overall survival in metastatic and locally advanced c-Kit positive gast...

Apart from its anti-inflammatory activity, which has been used for the treatment of active Crohn’s disease, thalidomide is also a potent inhibitor of angiogenesis. We therefore studied the effect of thalidomide in six patients with severe recurrent intestinal bleeding refractory to standard treatment (three patients with Crohn’s disease (CD), three patients with obscure intestinal bleeding; mea...