PURPOSE Mitochondrial dysfunction can present with various symptoms depending on the organ it has affected. This research tried to analyze the ophthalmologic symptoms and ophthalmologic examination (OE) results in patients with mitochondrial disease (MD). METHODS Seventy-four patients diagnosed with mitochondrial respiratory chain complex defect with biochemical enzyme assay were included in ...

BACKGROUND AND PURPOSE Structural connectivity has been thought to be a less sensitive measure of network changes relative to functional connectivity in children with localization-related epilepsy. The aims of this study were to investigate the structural networks in children with localization-related epilepsy and to assess the relation among structural connectivity, intelligence quotient, and ...

OBJECT Occipital lobe epilepsy (OLE) accounts for a small percentage of extratemporal epilepsies and only few and mostly small patient series have been reported. Preoperative findings, surgical strategies, histopathological bases, and postoperative outcomes for OLE remain to be elucidated. METHODS A group of 54 patients with occipital lobe involvement were identified from a prospective epilep...

Bye et al. in 1993 first described the pathological findings in a patient with celiac disease (CD), bilateral occipital calcifications, and drug-resistant epilepsy who became seizure-free after extensive occipital resection. We report a case with an identical anatomoclinical condition in which surgical removal of the circumscribed calcified lesion was ineffective and epilepsy worsened until a g...

In a patient with refractory temporal lobe epilepsy, EEG-fMRI showed activation in association with left anterior temporal interictal discharges, in the left temporal, parietal and occipital lobes. Dynamic causal modelling suggested propagation of neural activity from the temporal focus to the area of occipital activation. Tractography showed connections from the site of temporal lobe activatio...

Occipital lobe infarcts, hemorrhages, or metastatic tumors can present with complex visual hallucinations, sensory or proprioceptive abnormalities, speech dysfunction, visual loss, and homonymous hemianopia (HH). Treatment of occipital lobe seizures is by single or multiple antiepileptic drugs. We present a case of idiopathic occipital lobe epilepsy where the seizures were controlled by antiepi...

AIM To evaluate localization of certain zones of craniocerebral trauma and determine their importance for genesis ofposttraumatic epilepsy. PATIENTS AND METHODS Study encompassed 50 war veterans, with craniocerebral trauma and posttraumatic epilepsy. Control group included 50 war veterans, with war craniocerebral injury who have not experienced epileptic seizures. The craniocerebral trauma zo...

It is difficult to differentiate between seizures of occipital or temporal lobe origin in patients with focal epileptic seizures associated with visual aura. These are often suspected to originate from the visual cortex, which causes reluctance to propose resection as treatment for the affected patient. To determine the value of localizing different types of visual auras, we report on 20 patien...