background the occult hepatitis b infection (obi) is defined as the presence of hepatitis b virus (hbv) dna in the sera or in the liver biopsy and the absence of hepatitis b surface antigen (hbsag) by serological test. objectives the current study aimed to evaluate the occult hbv infection by polymerase chain reaction (pcr) and determine hbv genotyping among the patients with abnormal alanine t...

Recovery from an acute hepatitis B virus (HBV) infection is associated with loss of HBV DNA from serum, hepatitis B e antigen seroconversion, hepatitis B surface antigen (HBsAg) seroconversion, and normalization of serum aminotransferases. These changes generally imply clearance of virus, but clinical observations have shown that reactivation of HBV infection can occur either spontaneously or a...

background: blood transfusion plays a great role in public health and the blood safety still has remained a main concern. hbv has been considered as one of the most prevalent blood borne infections. it is estimated that chronic hbv affects 350-400 million people worldwide. comprehensive knowledge about hbv has high importance in iran due to high number of blood dependent patients. material and ...

Human immunodeficiency virus (HIV)- infected patients are at risk of acquiring viral hepatitis, due to common routes of transmission. As the introduction of highly active antiretroviral therapy (HAART) reduced the frequency of opportunistic infections and improved survival, viral hepatitis emerged as an important cause of morbidity and mortality in HIV-infected cases. Occult hepatitis B virus (...

BACKGROUND Co-infections of hepatitis B and C viruses are frequent with HIV due to shared routes of transmission. In most of the tertiary care health settings, HIV reactive patients are routinely tested for HBsAg and anti-HCV antibodies to rule out these co-infections. However, using the routine serological markers one can only detect active HBV infection while the occult HBV infection may be m...

background: the risk of infection by transfusion-transmitted viruses has been reduced remarkably. however, a zero-risk blood supply is still desirable. the screening for antibody to hbc (anti-hbc) has been shown as an alternative test for the detection of hbv infection. objective: the main aim of this study was to evaluate hbv infection markers and the potential value of anti-hbc testing of blo...

BACKGROUND & AIMS Occult hepatitis B virus (HBV) infection is a well-recognized clinical entity characterized by the detection of HBV DNA in serum and/or liver in the absence of detectable hepatitis B surface antigen (HBsAg). The frequency of the diagnosis depends on the relative sensitivity of both HBsAg and HBV DNA assays. We aimed at determining the prevalence of occult HBV infection in a hi...

BACKGROUND AND OBJECTIVE The aim of this study was to investigate the prevalence of occult hepatitis B virus (HBV) infection and the HBV surface (S) gene variants circulating in the South African population after nearly two decades of universal hepatitis B vaccination. STUDY DESIGN From a previous serosurvey, 201 serum samples with serological evidence of exposure to HBV were identified and t...

BACKGROUND Hepatitis B virus (HBV) infection is a worldwide public health problem. Nine HBV genotypes (A-I) have been already discovered. HBV genotypes are important both in the clinical manifestation of disease and treatment response. Moreover, HBV DNA without HBs (Hepatitis B surface)-antigenemia was detected in some patients with chronic hepatitis (occult hepatitis). There is little informat...

The prevalence of occult Hepatitis B virus (HBV) infection in children was considerably varied from 0.1-64% in different reports. In this study we aimed to investigate the prevalence of occult HBV infection among the children born to mothers with positive hepatitis B surface antigen (HBsAg) in Jiangsu, China. Serum samples were collected from 210 children of 207 mothers with positive HBsAg. HBV...