Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, 8 Department of Environmental and Occupational Health, School of Public Health, 9 Rutgers University, Piscataway, New Jersey 08854 and 10 Drug Safety Sciences, Johnson & Johnson, Raritan, NJ 08869 11 12 Corresponding author: 13 Dr. Debra L. Laskin 14 Department of Pharmacology and Toxicology 15 Ernest Mario School of Ph...

BACKGROUND The pharmaceutical industry employs >350 000 people worldwide in operations including research and development (R&D), manufacturing, sales and marketing. Workers employed in R&D and manufacturing sectors are potentially exposed to drug substances in the workplace that are designed to modify physiology and also to chemical precursors that are potentially hazardous to health. Pharmaceu...

The National Institute of Environmental Health Sciences (NIEHS) has several new initiatives involving chemical mixtures and has recognized the need to develop new experimental approaches to enhance our efforts in this area. Responding to recent increases in nominations of complex occupational exposures for toxicologic assessment by the U.S. National Toxicology Program, the NIEHS and the Nationa...

* Narcotic Analysis and Technical Service Institute, Office of the Narcotics Control Board, Ministry of Justice, Bangkok, Thailand ** Department of Occupational Health and Safety, Faculty of Public Health, Centre for Environmental Health, Toxicology and Management of Chemicals (ETM), Mahidol University, Bangkok, Thailand *** Department of Biostatistics, Faculty of Public Health, Mahidol Univers...

Xiaoqing He and Qiang Ma Receptor Biology Laboratory, Toxicology and Molecular Biology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention (X.H., Q.M.); Department of Biochemistry, West Virginia University School of Medicine (Q.M.), Morgantown, WV JPET Fast Forward. Published on October 6, 2009 as DOI:10.1...

* Department of Occupational Health and Safety, Faculty of Public Health, Centre for Environmental Health, Toxicology and Management of Chemicals (ETM), Mahidol University, Bangkok, Thailand ** Narcotic Analysis and Technical Service Institute, Office of the Narcotics Control Board, Ministry of Justice, Bangkok, Thailand *** Department of Biostatistics, Faculty of Public Health, Mahidol Univers...

The California OSHA Airborne Contaminant Advisory Committee reviewed several hundred substances and recommended occupational exposure limits with the intent of worker and employer protection. The model used offers important benefits. First, by allowing open meetings, the process was transparent, and input could be offered by concerned stakeholders. Second, the process was data-driven and, there...

BACKGROUND AND OBJECTIVE The progressive increase in cases of multiple chemical sensitivity (MCS) syndrome and the lack of studies which associate the syndrome with possible occupational origins means that further research in this field is required. The objective of this study was to compare the epidemiological, clinical and prognostic aspects of cases of MCS of occupational and non-occupationa...

OBJECTIVES Wood dust is a known occupational allergen that may induce, in exposed workers, respiratory diseases including asthma and allergic rhinitis. Samba (obeche, Triplochiton scleroxylon) is a tropical tree, which grows in West Africa, therefore, Polish workers are rarely exposed to it. This paper describes a case of occupational asthma caused by samba wood dust. MATERIAL AND METHODS The...