Background: In several conditions we have face cranial bone defects. Reconstruction of these defects remains one of the most challenging problems encountered by craniofacial surgeons. Objective: To evaluate bone repair in cranial bone defects by use of an implant made of octacalcium phosphate in combination with bone matrix gelatin (OCP/BMG). Methods: We used 40, 5–6-week-old male Sprague-Dawle...

Lesions involving the osteochondral unit are difficult to treat. Biomimetic scaffolds previously shown as promising alternative. Such devices often lack multiple functional layers that mimic bone, cartilage, and interface. In this study, multilayered developed based on use of natural extracellular matrix (ECM)-like biopolymers. Particular attention is paid obtain a complex mimics native transit...

This article presents the results of a study radiation-induced defects in various synthetic calcium phosphate (CP) powder materials (hydroxyapatite—HA and octacalcium phosphate—OCP) by electron paramagnetic resonance (EPR) spectroscopy at X, Q, W-bands (9, 34, 95 GHz for microwave frequencies, respectively). Currently, CP are widely used orthopedics dentistry owing to their high biocompatibilit...

Octacalcium phosphate (OCP) and hydroxyapatite (HAp) coatings were developed to control the degradation speed and to improve the biocompatibility of biodegradable magnesium alloys. Osteoblast MG-63 was cultured directly on OCP- and HAp-coated Mg-3Al-1Zn (wt%, AZ31) alloy (OCP- and HAp-AZ31) to evaluate cell compatibility. Cell proliferation was remarkably improved with OCP and HAp coatings whic...

Real-time, in situ electrochemical quartz crystal microbalance (EQCM) measurements are conducted to better understand the electrocrystallization of calcium phosphates (CaP) on CP-Ti. X-ray photoelectron spectroscopy is used to identify the exact phase deposited, so that reliable estimation of the electrochemical processes involved is made. Analysis of the integrated intensity of the oxygen shak...

acceptor/donor or Lewis acid-base (AB) terms, in regulating not only the rates of these reactions but also in determining the solubility behavior of the crystal, S,. For a considerable number of compounds, the solubilities show a general increase as the solidlliquid interfacial tensions (~sL) decrease, but despite suggestions to the contrary, the relationship between ysL and logs, should not ne...

The interest in electrocrystallization of calcium phosphates (CaP) in general, and of hydroxyapatite (HAp) specifically, results from the promising industrial benefits, unique microstructures, and properties of the deposits produced by this process, and the possible similarity to bone mineralization in vivo. In this paper, our work on electrocrystallization of HAp and octacalcium phosphate (OCP...

Many questions remain regarding the formation of ultrathin hydroxapatite (HAP) crystals within the confines of collagen fibrils of bones. These structures form through the interplay of the collagen matrix and non-collagenous proteins, and in vitro mineralization studies employing poly(aspartic acid) (PAsp) as a mimic of the non-collagenous proteins have generated mineralized fibrils with struct...