Leishmaniasis is a zoonotic parasitic disease that affects both humans and animals. Canines are considered the main reservoirs of disease, while cats can present as secondary reservoirs, altering epidemiological cycle disease. The work describes first case feline foot hyperkeratosis in Asunción-Paraguay associated with leishmaniasis, determined by cytological diagnosis, favorable response to tr...

Leishmaniasis is a wide-spectrum disease caused by parasites from Leishmania genus. A well-modulated immune response that established after the long-lasting clinical cure of leishmaniasis can represent standard requirement for vaccine. Previous studies demonstrated (Viannia) naiffi causes benign and its antigens induce responses in vitro. In this work we aimed to identify immunodominant protein...

Diffuse cutaneous leishmaniasis is a rare form of characterized by an inadequate immune response the host cells to parasitic invasion (weak T-helper (Th)1 or Th2 with production interleukin (IL)-4 and IL-10). The characteristic features disease include diffuse nodular eruption, masquerading as leprosy frequent association immunosuppression (HIV co-infection, for example). Russian Federation non...

ABSTRACT: Visceral leishmaniasis is the most severe form of a human and animal disease complex entitled leishmaniasis, which endemic to 70 countries. It imperative develop offer technologies capable increasing resolution ability control programs this zoonosis. In search for technological innovations in health, especially environmental surveillance, objective mobile application (App) smartphones...

BACKGROUND Disseminated leishmaniasis is an emerging infectious disease, mostly due to L. braziliensis, which has clinical and histopathological features distinct from cutaneous leishmaniasis. METHODS In the current study we evaluated the in vitro production of the cytokines IFN-gamma, TNF-alpha, IL-5 and IL-10 by peripheral blood mononuclear cells (PBMC) from 15 disseminated leishmaniasis an...

purpose: controversy has recently risen about the presence of compensatory ocular countertorsion (coct) after head tilt. this study was performed to define the functional range of this phenomenon. methods: cycloplegic autorefraction was performed on 80 eyes with regular astigmatism 2d. objective autorefraction was performed in normal position, right and left head tilt positions of 5º, 10º, 15º,...

HIV infection leads to worse treatment outcomes in visceral leishmaniasis (VL) and increases the risk of post-treatment relapse, suggesting that similar effects may be observed in other low CD4 T cell states [1]. Idiopathic CD4 T cell lymphocytopenia (ICL) was first described in 1992 in the setting of the emerging HIV pandemic [2]. It is a rare condition defined as a CD4 T cell count persistent...

Canine visceral leishmaniasis has been denoted as neglected despite being a very well-known disease. Trace element alteration recognized in humans with and cutaneous leishmaniasis, together canine leishmaniasis. The trace elements occupy vital position the immunological system, host immune responses mitigate defense against We aimed to select total of 45 dogs several breeds; those at age 11 mon...