نتایج جستجو برای: omv adjuvant
تعداد نتایج: 44182 فیلتر نتایج به سال:
Nanopods are extracellular structures arising from the convergence of two widely distributed bacterial characteristics: production of outer membrane vesicles (OMV) and formation of surface layers (S-layers). Nanopod production is driven by OMV formation, and in Delftia acidovorans Cs1-4 growth on phenanthrene induces OMV/nanopod formation. While OMV production has been associated with many func...
(-)-O-Methylvesamicol ((-)-OMV) exhibited in vitro a high affinity for vesicular acetylcholine transporter (VAChT) (Ki, 6.7 nM) and a relatively low affinity for sigmal receptor (Ki, 33.7 nM). We prepared (-)-[11C]OMV by a palladium-promoted cross-coupling reaction using [11C]methyl iodide, in a radiochemical yield of 38 +/- 6.9% (n=3), a radiochemical purity of 98 +/- 2.3% (n = 5), and a speci...
We have isolated and purified outer membrane vesicles (OMV) from Borrelia burgdorferi strain B31 based on methods developed for isolation of Treponema pallidum OMV. Purified OMV exhibited distinct porin activities with conductances of 0.6 and 12.6 nano-Siemen and had no detectable beta-NADH oxidase activity indicating their outer membrane origin and their lack of inner membrane contamination, r...
Rapid detection and quantification of outer membrane vesicle (OMV) are both scientific value clinical implications. However, limited tools available for investigations OMVs. Herein, we report a novel fluorescent probe with aggregation-induced emission (AIE) characteristics, namely, OEO-TPE-MEM (OTM), OMV detection. OTM emits faintly in an aqueous medium, but its fluorescence could be effectivel...
We previously reported that mutation of galE in Porphyromonas gingivalis has pleiotropic effects, including a truncated lipopolysaccharide (LPS) O-antigen and deglycosylation of the outer membrane protein OMP85 homolog. In the present study, further analysis of the galE mutant revealed that it produced little or no outer membrane vesicles (OMVs). Using three mouse antisera raised against whole ...
Immune responses to the gonococcus after natural infection ordinarily result in little immunity to reinfection, due to antigenic variation of the gonococcus, and redirection or suppression of immune responses. Brinton and colleagues demonstrated that parenteral immunization of male human volunteers with a purified pilus vaccine gave partial protection against infection by the homologous strain....
سابقه و هدف: واکسن های پلی ساکاریدی نیسریا مننژیتیدیس سروگروهa به علت ایجاد پاسخ های مستقل از لنفوسیت t دارای معایبی هستند. در نتیجه پژوهش های زیادی برای جایگزین کردن آنها با اجزاء دیگر باکتری انجام شده است که می توان به وزیکول غشاء خارجی ((omv حاوی pora اشاره کرد. در پژوهش حاضر، پس از استخراج و ارزیابی بیولوژیکی omv نیسریامننژیتیدیس سروگروهa ،توان القاء سنتز آنتی بادی بر علیه آن در حیوان آزمای...
BACKGROUND Vibrio cholerae excreted by cholera patients is "hyperinfectious" (HI), which can be modeled by passage through infant mice. Immunization of adult female mice with V. cholerae outer-membrane vesicles (OMVs) passively protects suckling mice from challenge. Although V. cholerae is unable to colonize protected pups, the bacteria survive passage and have the potential to be transmitted t...
هموفیلوس آنفلوانزا تیپ b (hib) یکی از علل اصلی مننژیت و پنومونی در نوزادان و کودکان در کشورهای در حال توسعه است و هرساله حداقل 3 میلیون مورد بیماری ناشی از hib در سراسر جهان ایجاد می شود. کپسول پلی ساکاریدی hib، پلی ریبوزیل ریبیتول فسفات (prp) فاکتور اصلی بیماریزایی می باشد. کپسول پلی ساکارید کونژوگه شده به پروتئین حامل در پیشگیری از عفونت ها موثر است. میزان شیوع عفونت های ناشی از hib در ایران ...
UNLABELLED Gram-negative bacteria naturally produce outer membrane vesicles (OMVs) that arise through bulging and pinching off of the outer membrane. OMVs have several biological functions for bacteria, most notably as trafficking vehicles for toxins, antimicrobials, and signaling molecules. While their biological roles are now appreciated, the mechanism of OMV formation has not been fully eluc...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید