BackgroundFor adolescents with suspected polycystic ovary syndrome (PCOS) and severely elevated testosterone concentrations, imaging is recommended to assess for neoplasm. Selective venous sampling (SVS) can be considered when nondiagnostic.CaseAn adolescent female treated PCOS had a peak of 344 ng/dL (11.9 nmol/L). Imaging did not localize mass. SVS implicated the right as source hyperandrogen...

A postal questionnaire was sent to all gynaecological consultants and senior registrars (n = 50) in Northern Ireland to establish the prevalence of prophylactic oophorectomy. Forty three (84%) replied. 72% performed prophylactic oophorectomy (28% unilateral), 28% did not. With reference to the world literature, there appears to be no benefit from the unilateral procedure but a consensus that bi...

Risk-reducing salpingo-oophorectomy for reducing future cancer risk in women with hereditary breast and ovarian cancer syndrome is rarely performed in Japan; therefore, the cancer preventive effect of risk-reducing salpingo-oophorectomy for hereditary breast and ovarian cancer syndrome among the Japanese population remains unclear. Here, we report the first case of serous tubal intraepithelial ...

BACKGROUND Risk-reducing salpingo-oophorectomy is currently regarded as the most certain primary method for preventing ovarian cancer among BRCA1/2 mutation carriers with hereditary breast and ovarian cancer syndrome. However, risk-reducing salpingo-oophorectomy has rarely been performed in Japan. METHODS We developed the first system in Japan for performing risk-reducing salpingo-oophorectom...

Hysterectomy for benign gynecological diseases is a common surgical procedure. Prophylactic bilateral oophorectomy is often recommended concurrent with hysterectomy to decrease the risk of ovarian cancer. Oophorectomy before menopause leads to an abrupt decrease in endogenous estrogen and androgen production leading to different health problems. So women undergoing hysterectomy for benign gynec...

With great interest we read the article by Zhai et al. [1] in the June 2012 issue of the Journal of Pediatric Surgery regarding gonadal function after childhood ovarian surgery. The authors show that unilateral oophorectomy compared to ovarian salvage does not appear to impair late gonadal function after childhood ovarian surgery. Interestingly, they observed that unilateral oophorectomy appear...

OBJECTIVE To review the clinicopathological characteristics of ovarian masses in Korean premenarchal girls. DESIGN The data collected from hospital medical records were reviewed retrospectively regarding age, presentation, diagnosis, treatment, and outcome. PARTICIPANTS There were 65 premenarcheal girls who underwent surgery at Seoul St. Mary's Hospital between January 1990 and March 2012. ...

BACKGROUND The long-term cognitive effects of hysterectomy and oophorectomy remain controversial. OBJECTIVE To explore the association of hysterectomy and oophorectomy with the subsequent risk of cognitive impairment or dementia. METHODS We combined the results from two cohort studies graphically and conducted additional analyses. RESULTS Combined results from the Mayo Clinic Cohort Study...