In this paper, an enhancement design of communication system using optical radio frequency (RF) waves in free space optical communication (FSO) system is presented. To our knowledge, it is the first time that the effect of Gamma-Gamma turbulent channel model on the performance of the proposed system is analyzed and simulated. To obtain an optical communication system with good performance and h...

We briefly review a recent technological development for simultaneous optical stimulation and optical imaging of activation in cardiac tissue. Such alloptical system for interrogation of cardiac electrophysiology can facilitate the study of arrhythmias and the development of a new generation of optical pacemakers. Key elements in the system included the biological integration of light-sensitive...

Spectrally encoded confocal microscopy and optical frequency domain imaging are two non-contact optical imaging technologies that provide images of tissue cellular and architectural morphology, which are both used for histopathological diagnosis. Although spectrally encoded confocal microscopy has better transverse resolution than optical frequency domain imaging, optical frequency domain imagi...

A novel optical frequency-domain imaging system is demonstrated that employs a passive optical demodulation circuit and a chirped digital acquisition clock derived from a voltage-controlled oscillator. The demodulation circuit allows the separation of signals from positive and negative depths to better than 50 dB, thereby eliminating depth degeneracy and doubling the imaging depth range. Our sy...

Diffuse optical imaging is highly versatile and has a very broad range of applications in biology and medicine. It covers diffuse optical tomography, fluorescence diffuse optical tomography, bioluminescence, and a number of other new imaging methods. These methods of diffuse optical imaging have diversified instrument configurations but share the same core physical principle - light propagation...

The IVIS® SpectrumCT is a powerful and versatile optical imaging platform for small animal imaging in pre-clinical settings. With a relatively small floor footprint, it provides two key optical imaging functionalities: Bioluminescence (BLI) and Fluorescence (FLI). Its advanced optical components, including an ultra-sensitive CCD camera and two full range excitation/emission filter sets, enable ...

During the past decade, optical imaging through scattering medium has proved to be a powerful technique for many applications. It is especially effective in medical diagnostic, since it is safe, noninvasive and low-cost compared with the conventional radiation techniques. Based on a similar principle of the fly's visual system, we show a novel method of optical imaging through scattering medium...

We experimentally demonstrate the feasibility of a super-resolution technique based on eigenmode decomposition. This technique has been proposed theoretically but, to the best of our knowledge, has not previously been realized experimentally for optical imaging systems with circular apertures. We use a standard diffraction-limited 4f imaging system with circular apertures for which the radial e...

The adoption of a short source-detector distance, combined with a time-resolved acquisition, can be advantageous in diffuse optical imaging due to the stricter spatial localization of the probing photons, provided that the strong burst of early photons is suppressed using a time-gated detection scheme. We propose a model for predicting the effect of the time-gated measurement system using a tim...

Fluorescence-enhanced optical tomography is typically performed using single point illumination and multiple point collection measurement geometry. Single point illumination is often insufficient to illuminate greater volumes of large phantoms and results in an inadequate fluorescent signal to noise ratio (SNR) for the majority of measurements. In this work, the use of simultaneous multiple poi...