Objective. The aim of this study was to quantitatively evaluate the salivary tumor necrosis factor-alpha (TNF-α) level in oral lichen planus patients and to compare the levels of TNF-α between saliva and serum of OLP and controls. Methods. Serum and whole saliva from 30 patients with active lesions of oral lichen planus (OLP) and 30 healthy persons were investigated for the presence of TNF-α by...

BACKGROUND AND AIM: Oral lichen planus (OLP) is a chronic, autoimmune, inflammatory disease. The progression of OLP to oral squamous cell carcinoma (OSCC) has generated a longstanding controversy about the details of this malignant transformation potential. This study aimed to do a systematic review on the molecular markers related to the malignant transformation of OLP.METHODS: We searched the...

conclusions this study showed that topical glycyrrhiza glabra appeared to be a promising alternative in the treatment of olp. further studies should be conducted to assess the long-term effects of glycyrrhiza glabra. objectives the aim of this study was to compare the efficacy and safety of 1% glycyrrhiza glabra in orabase with 0.1% triamcinolone acetonide paste in treating oral lichen planus (...

Background: Lichen planus is a T-cell mediated autoimmune and chronic inflammatory disease that affects the skin and the mucous membrane. The results of numerous studies on oral mucosa have confirmed the effects of sex hormones on oral mucosa and the expression of estrogen (ER), progesterone (PR), and androgen receptors. Lichen planus is a common disease in middle-aged wo...

We read with great interest the article, “Hepatitis C virus and Lichen Planus: The real association” by Mahboobi et al. (1) because our practice serves a large group of patients with Oral Lichen Planus (OLP). OLP has been associated with chronic liver diseases, particularly those that have Hepatitis C Virus (HCV) (2) as a possible etiology. The association between HCV and Lichen Planus has been...

Oral lichen planus (OLP) is a chronic mucosal condition commonly encountered in clinical dental practice. Lichen planus is believed to represent an abnormal immune response in which epithelial cells are recognized as foreign, secondary to changes in the antigenicity of the cell surface. It has various oral manifestations, the reticular form being the most common. The erosive and atrophic forms ...

Oral lichen planus (OLP) is a relatively common chronic immunologic mucocutaneous disorder. Although there are many presenting treatments, some of them proved its failure. Recently, the use of photodynamic therapy (PDT) has been expanding due to its numerous advantages, as it is safe, convenient, and non-invasive and has toxic effect towards selective tissues. This article provides comprehensiv...

Lichen planus (LP) is a chronic inflammatory mucocutaneous disease of unknown aetiology with an estimated incidence 0.5%–4.0% having female preponderance at ratio 1.5:1. Oral lichen (OLP) commoner than the cutaneous form and tends to be more persistent refractory treatment. The prevalence oral in Indian population around 3% predilection. lesions occur 50%–70% patients planus. LP considered T-ce...

Abstract Introduction Oral lichen planus (OLP) is a chronic inflammatory disorder with cell‐induced immunopathological responses and considered potential malignancy in the oral cavity. Due to high prevalence of OLP as well for malignancy, human papillomaviruses (HPVs) may play an important role it. Although previous studies have explored possible relationship between HPV OLP, findings been conf...

STATEMENT OF PROBLEM Lichen planus is a chronic inflammatory immunologic-based disease involving skin and mucosa. This disease is generally divided into two categories: erosive and non-erosive. Many etiologic factors are deliberated regarding the disease; however, the disorders of immune system and the role of cytotoxic T-lymphocytes and monocytes are more highlighted. Zinc is an imperative ele...