Spindle cell Carcinoma is a rare biphasic neoplasm consisting of epithelial and mesenchymal components and accounts for less than 1% of all tumours of oral region. It is a rare aggressive variant of squamous cell carcinoma which frequently recurs and metastasizes with poor prognosis compared to classical squamous cell carcinoma. The biologic behaviour is comparable to poorly differentiated Squa...

introduction: choristoma is defined as the presence of cells in abnormal locations due to defects during embryological development. the word choristoma implies a neoplasm; whereas heterotopia refers to a displaced tissue without necessarily being a swelling or a neoplasm. literature contains reports of cartilaginous choristoma in the cervix, endometrium, breast tissue, and oral region.   case r...

Adenomatoid odontogenic tumor is a non-aggressive slow growing epithelial odontogenic tumor with varied clinical and microscopic features. This neoplasm rarely appears as a completely cystic lesion histopathologically; therefore, oral pathologists should be aware of the various histopathologic types of this lesion. The main objective of this case report is to present a rare challenging case o...

We present a rare case of intraoral nerve sheath myxoma. Clinically, the neoplasm mimics many other oral mucosal pathosis, underscoring the importance of histopathology in ensuring accurate diagnosis of oral mucosal lesions. Reports of intraoral nerve sheath myxomas are essential to enhance our understanding of this rare intraoral entity.

Primary malignant melanoma of the oral cavity is a rare neoplasm. The tumors tend to metastasize or locally invade tissue more readily than other malignant tumors in the oral region. The survival of patients with mucosal melanomas is less than for those with cutaneous melanomas. Tumor size and metastases are related to the prognosis of the disease. Early detection, therefore, is important.

Granular cell tumor (GCT) is an uncommon neoplasm of controversial origin that can appear in any corporal localization, including the orofacial region. Although aggressive and malignant variants of this neoplasm have been described, most of GCTs are benign. In spite of the amount of research, the etiology of this neoplasm remains unclear and its histogenesis and its possible muscular, connectiv...

oral cancer is a common neoplasm world-wide. the incidence and mortality have increased over the past decades. it is characterized by poor prognosis and a low survival rate despite sophisticated surgical and radiotherapeutic modalities. galectins are detected in a wide variety of tissues. the expression of galectins is modulated during the differentiation of individual cells and during the deve...

Osteoblastoma is a rare solitary osteoblastic bone neoplasm. It is characterized by proliferation of osteoblasts forming trabeculae within a vascular fibrous stroma. There is a variety of jaw bone lesions with very close clinical, radiological and microscopic interrelations, which make diagnosis more challenging. Familiarity with these rare bony lesions is vital for oral pathologists. This repo...

To evaluate the role of high-dose dietary zinc in the process of prostate malignancy, 60 Sprague-Dawley rats were randomly divided into four groups: tumor induction with carcinogen and hormone (group 1), oral zinc administration without tumor induction (group 2), oral zinc administration with tumor induction (group 3) and a control without zinc administration or tumor induction (group 4). Zinc ...

  Introduction: Choristoma is defined as the presence of cells in abnormal locations due to defects during embryological development. The word choristoma implies a neoplasm; whereas heterotopia refers to a displaced tissue without necessarily being a swelling or a neoplasm. Literature contains reports of cartilaginous choristoma in the cervix, endometrium, breast tissue, and oral region.   ...