The purpose of this study was to determine the effect of aging on the tactile and pain sensitivity, and the factors influencing threshold change in the oral mucosa using Semmes-Weinstein Pressure Aesthesiometer. The touch and pain thresholds of 81 healthy elderly (40 males and 41 females, 77 +/- 4.5 years) were compared with those of 58 young volunteers (27 males and 31 females, 27 +/- 2.5 year...

The aim of this study was to evaluate whether age of onset of multiple sclerosis is related to use of combined oral contraceptives and/or timing of childbirth. The results showed that use of combined oral contraceptives and childbirth before the first multiple sclerosis symptom was correlated to a higher mean age at the onset of the disease.

OBJECTIVES Associations between khat (Catha edulis) chewing and different adverse oral-dental health conditions have been reported, yet evidence is still lacking. This study was designed to investigate the association between long-term regular khat chewing and self-reported oral symptoms. METHODS A cross-sectional study was conducted on a sample of 1,255 university students in southern Ethiop...

Intranasal flunisolide is an effective treatment for allergic rhinitis. Flunisolide has high bioavailability when administered to normal subjects (50% of an intranasal dose reaches the systemic circulation) with minimal systemic effects. Bioavailability in patients with active rhinitis averages 62.4 +/- 15.7%. The oral dose bioequivalent to 100 micrograms intranasally is 500 micrograms. To defi...

objective(s): drug addiction is one of the fastest growing social problems that researchers, for many years, have been trying to find proper strategies for its prevention and treatment. short-term physical activity is considered as acceptable for the treatment and prevention of addiction. on the other hand, prefrontal cortex is known to be responsible for many of the complex behavioral response...

BACKGROUND Dry mouth is very common symptom, and psychological factors have an influence on this symptom. Although the influence of emotional factor related to patients with oral dryness has been examined in previous studies, the cognitive factors have not been examined thus far. OBJECTIVE The purpose of this study was to examine the influence of cognitive factors on patients with oral drynes...

background medical sphincterotomy has gained popularity as a treatment for anal fissure. calcium channel blockers in topical forms could also be appropriate with low adverse effects. objectives this was a prospective randomized controlled trial to compare topical and oral nifedipine in the treatment of chronic anal fissure. patients and methods a prospective randomized controlled trial was cond...

Metastasis to the oral region is very rare and accounts for less than 1% of oral malignant tumors. Breast, lung, kidney, adrenal, gastro intestinal tract and prostates are most common primary tumors from which metastasis to oral region occur frequently. Metastasis from thyroid gland is extremely rare to oral region. We present an unusual case of metastatic follicular carcinoma of thyroid in max...