The existence of multipotent adipose-derived stem cells isolated from human orbital fat (OF) tissue has shown great therapeutic potential in tissue engineering and regenerative medicine. But the use of stem cells for therapeutic applications is influenced by their proliferative and differentiation potentials, which may be affected by the age of the donor. So far there is little knowledge about ...

PURPOSE To establish guidelines for interpretation of orbital imaging by magnetic resonance imaging (MRI) and/or computed tomography (CT), and to apply these guidelines and examine their predictive value in 131 patients with biopsy-proven orbital tumors. DESIGN Prospective evaluation of imaging studies. PARTICIPANTS Imaging studies (CT and/or MRI) from 131 cases with biopsy-proven orbital t...

PURPOSE The aim of the study described here was to report the outcomes of surgery for orbital fat prolapse by conjunctival fixation to the sclera. PATIENTS AND METHODS Twenty-three consecutive eyes of 19 patients with orbital fat prolapse were retrospectively reviewed. All cases were treated with the same simple procedure without resection through conjunctival incision: fixation of conjunctiv...

OBJECTIVE To evaluate the ability of orbital apex crowding volume measurements calculated with multidetector-computed tomography to detect dysthyroid optic neuropathy. METHODS Ninety-three patients with Graves' orbitopathy were studied prospectively. All of the patients underwent a complete neuro-ophthalmic examination and computed tomography scanning. Volumetric measurements were calculated ...

A 75-year-old woman presented with six months history of progressing lagophthalmos and immobility of the left eye. Magnetic resonance imaging (MRI) of the orbit demonstrated infiltration of orbital fat and the extra-ocular muscles. We performed transverse blepharotomy of the left eyelid to correct lagophthalmos; and during surgery, we took a biopsy sample from levator muscle and orbital fat. Af...

ORBITAL pseudotumour is a term used to describe diverse clinical conditions which initially may simulate true orbital tumours but subsequently pursue a benign course. Although the first case was described over a century ago, a survey of the literature reveals little progress in the understanding of the processes involved in the production of pseudotumours. Many ofthe lesions are described as ch...

Transcutaneous lower blepharoplasty addresses excess skin, muscle, and fat through an infraciliary cutaneous incision. This approach offers excellent exposure to the fat pads; however, violation of the orbital septum may result in postoperative lower eyelid retraction, with resultant aesthetic disfigurement as well as exposure keratoconjunctivitis.1 The transconjunctival approach to lower bleph...

A chief morbidity of Graves eye disease is eyelid retraction and exophthalmus. Transpalpebral orbital fat removal accomplished with full thickness anterior blepharotomy was performed in 4 patients (5 orbits). Preoperative and postoperative ocular exposure symptoms, visual acuity, upper eyelid retraction and proptosis were evaluated. In all 5 operated orbits preoperative symptoms resolved; good ...

The human eye is a biomechanical system. Orbital fat plays an important rol in the working of this system, but its behaviour during eye movement is not well understood. To give insight into this behaviour, visualisation is a useful tool. This paper presents a complete pipeline for interactive particle-based visualisation and exploration of orbital fat deformation from MRI data. Sensible 3D part...