Background Recent studies have shown that there is an increased risk of Epithelial Ovarian Cancer (EOC) with Organochlorine Pesticides (OCPs). However, the alteration in the gene expression profile has not been explored so far. The goal of the present study is to understand the probable molecular mechanism of OCPs toxicity towards discovery of dysregulation of signaling pathway associated with ...

Persistent organic pollutants, (POPs), are vast distributed compounds in environment which are recognized as one of the global pollution problems. These groups of materials being dangerous due to their high stability are accumulated in animal tissues and occurring in the food chain. One of the major paths through which persistent organic combinations access to human body is consuming polluted f...

Persistent organic pollutants, (POPs), are vast distributed compounds in environment which are recognized as one of the global pollution problems. These groups of materials being dangerous due to their high stability are accumulated in animal tissues and occurring in the food chain. One of the major paths through which persistent organic combinations access to human body is consuming polluted f...

BACKGROUND Polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) are neurodevelopmental toxicants, but few studies have examined associations with autism spectrum disorder (ASD). OBJECTIVES We aimed to determine whether prenatal exposure to PCBs and OCPs influences offspring risk of ASD and intellectual disability without autism (ID). METHODS We conducted a population-based ...

Five species of macroalgae, namely Sargassum wightii, Padina tetrastromatica, Ulva lactuca, Caulerpa racemosa and Gracilaria edulis collected from three sampling sites, viz. Harbour Beach (site 1), Tharuvaikkulam 2) Hare Island 3), situated along the Thoothukudi region Gulf Mannar were analysed for 17 organochlorine pesticides (OCPs) by gas chromatography-mass spectrometry (GC-MS) to assess the...

p,p'-dichlorodiphenyldichloroethylene (p, p'-DDE) and β-hexachlorocyclohexane (β-HCH) were two predominant organochlorine pesticides (OCPs) metabolites in human body associated with disorders of fatty acid metabolism. However, the underlying mechanisms have not been fully clarified. In this study, adult male C57BL/6 mice were exposed to low dose of p, p'-DDE and β-HCH for 8 wk. OCPs accumulatio...

Brominated flame retardants (BFRs) represented by polybrominated diphenyl ethers (PBDEs) and hexabromocyclododecane (HBCD) together with major persistent organochlorine pollutants, polychlorinated biphenyls (PCBs) and selected organochlorine pesticides (OCPs), were determined in adipose tissue samples (n=98) obtained by liposuction of Czech subjects. Compared to other organochlorine pollutants ...

It is known that the consumption of seafood has several health benefits for humans. However, accumulation organic pollutants, such as polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs), in their flesh could pose public problems. Thus, concentrations PCBs OCPs edible fish species (Mugil bananensis, Sarotherodon melanotheron) from Sine Saloum Estuary located central-western Sen...

Fish and mollusk samples were collected from markets located in 12 cities in Liaoning province, China, during August and September 2007, and 22 organochlorine pesticides (OCPs) were detected. DDT, HCH, endosulfan, chlordane, and HCB were the dominating OCPs, with mean concentrations and ranges of, respectively, 15.41 and 0.57 to 177.56 ng/g, 0.84 and below detection limit (BDL) to 22.99 ng/g, 1...

In the Chinese city of Wuchang, Heilongjiang Province, a survey was conducted to track concentrations and distributions several organic pollutants near drinking water reservoirs, such as conventional organochlorine pesticides (OCPs) currently in use (CUPs), including organophosphorus (OPPs) neutral herbicides (NHs). From October 2007 July 2008, total 32 pairs sediment samples were gathered exam...