ABSTACT OBJECTIVES: Myocardial blood flow (MBF) imaging is used in patients with suspected cardiac sarcoidosis, and also in stress/rest studies. The accuracy of MBF is dependent on imaging parameters such as new reconstruction methodologies. In this work, we aim to assess the impact of a novel PET reconstruction algorithm (Bayesian-penalized likelihood-BPL) on the values determined from the cal...

Abstract Objective In this study, we investigated the optimal reconstruction algorithm in fluorodeoxyglucose (FDG) positron emission tomography (PET) with a short acquisition time. Materials and Methods phantom six spheres filled FDG solution (sphere size: 6.23–37 mm; radioactivity ratio of to background = 8:1) placed National Electrical Manufacturers Association were evaluated. Image time was ...

(18)F-fluoro-deoxy-glucose ((18)F-FDG) positron emission tomography (PET) is one of the most sensitive and specific imaging modalities for the diagnosis of non-small cell lung cancer. A drawback of PET is that it requires several minutes of acquisition per bed position, which results in images being affected by respiratory blur. Respiratory gating techniques have been developed to deal with res...

Objective: The aim of this study was to evaluate the influences of reconstruction and attenuation correction on the differences in the radioactivity distributions in 123I brain SPECT obtained by the hybrid SPECT/CT device. Methods: We used the 3-dimensional (3D) brain phantom, which imitates the precise structure of gray mater, white matter and bone regions. It was filled with 123I solution (20...

We investigate a new, fast and provably convergent MAP reconstruction algorithm for emission tomography. The new algorithm, termed C-OSEM has its origin in the alternating algorithm derivation of the well known EM algorithm for emission tomography. In this re-derivation, the complete data explicitly enters the objective function as an unknown variable. While the entire complete data gets update...

Rigshospitalet, University of Copenhagen, Denmark For a quantitative analysis in positron emission tomography (PET) or single-photon emission computed tomography (SPECT), attenuation correction (AC) is mandatory. CTscans or transmission scans are common tools for determination of the attenuation μ-map, but in the case of a PET/MR hybrid system it is difficult to associate one of these scans. Ma...

UNLABELLED Iterative reconstruction techniques such as an ordered subsets-expectation maximization (OSEM) algorithm can easily incorporated various physical models of attenuation or scatter. We implemented OSEM reconstruction algorithm incorporating compensation for distance-dependent blurring due to the collimator in SPECT. The algorithm was examined by computer simulation to estimate the accu...

Site-specific investigations of the role of radiomics in cancer diagnosis and therapy are emerging. We evaluated the reproducibility of radiomic features extracted from 18 Flourine-fluorodeoxyglucose (18 F-FDG) PET images for three parameters: manual versus computer-aided segmentation methods, gray-level discretization, and PET image reconstruction algorithms. Our cohort consisted of pretreatme...

OBJECTIVES The aim of this study was to evaluate the influences of reconstruction and attenuation correction on the differences in the radioactivity distributions in (123)I brain SPECT obtained by the hybrid SPECT/CT device. METHODS We used the 3-dimensional (3D) brain phantom, which imitates the precise structure of gray matter, white matter and bone regions. It was filled with (123)I soluti...

UNLABELLED A crucial method for investigating patients with coronary artery disease (CAD) is the calculation of the left ventricular ejection fraction (LVEF). It is, consequently, imperative to precisely estimate the value of LVEF--a process that can be done with myocardial perfusion scintigraphy. Therefore, the present study aimed to establish and compare the estimation performance of the quan...