نتایج جستجو برای: osteoblastogenesis

تعداد نتایج: 460  

Journal: :International Journal of Molecular Medicine 2016

2017
Dongfeng Zhao Chenglong Wang Yongjian Zhao Bing Shu Youji Jia Shufen Liu Hongshen Wang Junli Chang Weiwei Dai Sheng Lu Qi Shi Yanping Yang Yan Zhang Yongjun Wang

The clinical evidence indicated that cyclophosphamide (CPD), one of the chemotherapy drugs, caused severe deteriorations in bones of cancer patients. However, the exact mechanisms by which CPD exerts effects on bone remodeling is not yet fully elucidated. Therefore, this study was performed to investigate the role and potential mechanism of CPD in osteoblastogenesis and osteoclastogenesis. Here...

2013
Wenjuan Bi Zhiyuan Gu Yuanna Zheng Xiao Zhang Jing Guo Gang Wu

OBJECTIVES Hypervitaminosis A and alcoholism can result in a low mineral density and compromised regenerative capacity of bone, thus delaying implant osteointegration. The inhibitory effect of all-trans retinoic acid on osteoblastogenesis is considered to be one of the mechanisms. We hypothesized that heterodimeric bone morphogenetic protein-2/7 could antagonize all-trans retinoic acid and enha...

Journal: :Proceedings of the National Academy of Sciences 2005

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