نتایج جستجو برای: oxazepam
تعداد نتایج: 192 فیلتر نتایج به سال:
Selective serotonin (5-HT) reuptake inhibitors (SSRIs) are used as a first-line treatment in depression. However, many depressed patients are also treated with benzodiazepines to alleviate increased anxiety and sleep disturbances normally associated with depression. Since benzodiazepines inhibit 5-HT neuronal firing activity, they might attenuate SSRI-induced increase in extracellular 5-HT leve...
1750 CUNICAL CHEMISTRY, Vol. 39, No. 8, 1993 pam, oxazepam, triazolam) or the antidepressants amitriptyline, clomipramine, demethyl domipramine, desipramine, imipramine, fluvoxamine, trimipramine; nortriptyline, however, interferes with norfluoxetine. Blood samples from patients treated with a combination of fluoxetine and benzodiazepines (bromazepam, alprazolam, temazepam, clorazepate dipotass...
We describe a method for simultaneous quantitation of diazepam and its metabolites, N-desmethyldiazepam and oxazepam, by reversed-phase liquid chromatography with ultraviolet detection at 254 nm. After extraction with chloroform at pH 11.0, the organic extract is evaporated, and the residue is reconstituted in a small volume of mobile-phase and chromatographed. Concentrations as low as 12 to 20...
background: the aim of this study was to evaluate and compare the clinical and electrocardiographic (ecg) manifestations of benzodiazepines (bzs). methods: in this retrospective study, all bz-poisoned patients hospitalized at loghman hakim hospital between september 2010 and march 2011 were evaluated. patients’ information including age, sex, time elapsed between the ingestion and presentat...
Psychotropics, especially benzodiazepines, are commonly prescribed worldwide. Poorly eliminated at wastewater treatment plants, they belong to a group of emerging contaminants. Due their interaction with the GABAA receptor, may affect function nervous system non-target organisms, such as aquatic organisms. The toxicity oxazepam, very frequently detected benzodiazepine in continental freshwater,...
Recent publications appear to have answered several important questions for valerian root: • Does valerian impair cognitive function or cause excessive sedation? • How does its efficacy compare to benzodiazepine drugs? • Is valerian safe and effective for children? In an Australian study, nine healthy volunteers received single doses of either valerian root {lOOOmg or 500mg), the drug triazolam...
Benzodiazepines possess a wide spectrum of valuable pharmacological effects and are among the leading drugs, commonly prescribed ones for various pathologies. Herein we describe continuous flow synthesis six benzodiazepines from aminobenzophenones: diazepam, fludiazepam, nordazepam, nitrazepam, clonazepam, oxazepam.
We hypothesized that the mouse liver tumor response to non-genotoxic carcinogens would involve some common early gene and protein expression changes that could ultimately be used to predict chemical hepatocarcinogenesis. In order to identify a panel of genes to test, we analyzed global differences in gene and protein expression in livers from B6C3F1 mice following dietary treatment with two rod...
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