Cervical stimulation induces two daily rhythmic prolactin surges, nocturnal and diurnal, which persist for several days. We have shown that a bolus injection of oxytocin initiates a similar prolactin rhythm, which persists despite low levels of oxytocin after injection. This suggests that oxytocin may trigger the cervical stimulation-induced rhythmic prolactin surges. To investigate this hypoth...

BACKGROUND Oxytocin is released in response to a meal. Further, mRNA for oxytocin and its receptor have been found throughout the gastrointestinal (GI) tract. The aim of this study was therefore to examine whether oxytocin, or the receptor antagonist atosiban, influence the gastric emptying. METHODS Ten healthy volunteers (five men) were examined regarding gastric emptying at three different ...

Oxytocin plays an important role in monogamous pairbonded female voles, but not in polygamous voles. Here we examined a socially monogamous cooperatively breeding primate where both sexes share in parental care and territory defense for within species variation in behavior and female and male oxytocin levels in 14 pairs of cotton-top tamarins (Saguinus oedipus). In order to obtain a stable chro...

Increasing evidence has shown adverse effects of loneliness on cardiometabolic health. Oxytocin been linked with social cognition and behaviour, however, recently also energy metabolism obesity suggesting that oxytocin may underlie common mechanisms bridging mental somatic traits. To clarify whether the system contributes to links between health loneliness, we calculated genetic contribution si...

ABSTRACT
 Introduction: Retained placenta is one of major cause for postpartum haemorrhage. Various medication and routes administration have been reported to increase spontaneous delivery prevent manual removal placenta. Purpose the study compare outcome between misoprostol oxytocin in management retained placenta.
 
 Method: literature searching was done 4 databases (Pubmed, Eb...

We addressed the question how long salivary oxytocin levels remain elevated after intranasal administration, and whether it makes a difference when 16 or 24 IU of oxytocin administration is used. Oxytocin levels were measured in saliva samples collected from 46 female participants right before intranasal administration (at 9:30 a.m.) of 16 IU (n = 18) or 24 IU (n = 10) of oxytocin, or a placebo...

Recent studies showed that oxytocin plays an important role in nociceptive modulation in the central nervous system. The present study was undertaken to investigate the role of oxytocin in antinociception in the nucleus raphe magnus (NRM) of rats and the possible interaction between oxytocin and the opioid systems. Intra-NRM injection of oxytocin induced dose-dependent increases in hindpaw with...

Introduction: The aim of the present study was to evaluate the effect of oxytocin on the angiogenesis and inflammatory parameters in air pouch model of inflammation. Methods: Inflammation was induced by injection of carrageenan into pouches in male Wistar rats. Oxytocin (4.25, 8.5 and 17 μg) was administered intra pouch at the same time as the carrageenan and then for 2 consecutive days. Af...

In the study of the relationship between structure and biological activity in the neurohypophysial hormones, oxytocin and vasopressin, attention has recently been focused in this and other laboratories on the chemical functional groups. Aside from peptide linkages, these chemical functional groups in oxytocin consist of a primary amino, a phenolic hydroxyl, three carboxamide groups, and a disul...

Yu-Feng Wang Pulsatile release of hormones and neurotransmitters is widespread in mammals and typical of oxytocin secretion during lactation. Sucklingevoked pulsatile release of oxytocin follows a transient activation of hypothalamic oxytocin neurons in a burst-like firing pattern and leads to a bolus release of oxytocin and milk ejections. Prostaglandin (PG), a nonhormonal messenger cytokine, ...