BACKGROUND Blood bank recommendations specify that Ringer's lactate solution (LR) should be avoided while transfusing blood. However, there are few studies either evaluating or quantifying increased coagulation during rapid infusion of LR and blood. DESIGN AND METHODS Whole blood (WB, n = 25) and packed red blood cells (PRBC, n = 26) were rapidly admixed with normal saline (NS), Lactate solut...

introduction: in a prospective study, we aimed to assess the value of enhanced rdw to predict sepsis and evaluate factors affecting length of icu stay and in-hospital mortality among sepsis patients. material and method: after exclusion of 27 patients, we included 160 adult patients with suspicious sepsis admitted at university affiliated hospital with 33 icu-beds from 2010 to 2012. nighty pati...

OBJECTIVE To show if blood salvage is indicated in all patients submitted to cardiovascular surgery with cardiopulmonary bypass. METHODS We studied 77 consecutive patients submitted to cardiac surgery with use of blood salvage and cardiopulmonary bypass from November 2010 to June 2012. The sample was divided in three groups, depending on the time of cardiopulmonary bypass. In group A, the tim...

OBJECTIVE To review the literature on the limitations and consequences of packed red blood cell transfusions, with particular attention to critically ill patients. METHODS The PubMed database of the National Library of Medicine was searched to find published articles on the indications, clinical utility, limitations, and consequences of red blood cell transfusion, especially in critically ill...

Later and colleagues presented the results from a non-sponsored, double-blind, randomised trial comparing the clinical outcomes for tranexamic acid and aprotinin [1]. They report that aprotinin significantly reduced bleeding in comparison with tranexamic acid, but there was no difference in the number of packed red blood cells. With regard to outcomes, they report no significant differences, bu...

reached 5 Loglo deplelion and lhe absolule number of \vhile blood cells in lhe posl-fillralion unilS is always less lhan 2 x 10.\ \vilh considerable safely in lhe prevenúon of lransfusion reaclions. SUMMARY. The reCen( developmen( of new fil(ers used for leucocy(e reduc(ion aims a( restric(ing the number of leucocy(es (O a threshold \vhe:-e their undesirable effec(S can be minimized or excludeá...

The kinetics of sodium, movement into human red blood cells has been studied in vivo with (24)Na. When human serum albumin(-131)I is used to measure the percentage of plasma trapped in the packed red blood cells after centrifugation, approximately 30 % of red blood cell sodium is found to equilibrate immediately with plasma. It is concluded that this immediately exchangeable compartment of red ...

BACKGROUND Accumulating evidence suggests that transfusion of packed red blood cells (PRBCs) stored for >14 days is associated with increased rates of sepsis, multiple organ dysfunction, and mortality in human patients. OBJECTIVE To determine if duration of PRBC storage has an effect on morbidity and mortality in dogs after transfusion. ANIMALS Dogs admitted to the Matthew J Ryan Veterinary...

A technic is described for the determination of the in vivo pH of red blood cell hemolysates. The meanarterial redcell pH of 20 normalsubjectswas7.19 with a rangeof 7.15 to 7.22. The fiducial probability at the 0.95 levelis 7.13 to 7.25. The mean difference in pH between plasmaandcellswas0.21, with a rangeof 0.15 to 0.23. It is suggested that changesin pH of erythrocytesmay reflect changesin ot...