OBJECTIVE To explore a new identification and protection method of the parathyroid gland in reoperation for thyroid diseases. METHOD 54 patients receiving reoperation for thyroid diseases were selected. The experiment group intraoperatively adopted carbon nanoparticles suspension for negative development of the parathyroid gland, whereas the control group did not use carbon nanoparticles susp...

A 60-year old woman with a history of nodular goiter was admitted to hospital. Fine needle aspiration cytology (FNAC) of dominant nodule was suspicious of papillary thyroid carcinoma. Preoperative serum calcium level was normal in biochemical analysis. Cervical exploration revealed an aberrant tissue inferior to left thyroid gland which was reminiscent of parathyroid adenoma or an enlarged lymp...

1) In the absence of the thyroid gland, the infusion of parathyroid hormone leads to a prompt rise in plasma calcium and to prompt increase in the rate of excretion of calcium in the urine.2) In the presence of the thyroid gland, the parathyroid hormone-induced rise in plasma calcium is less marked; the rate of urinary calcium excretion falls initially and rises only after 20 to 30 hours of con...

This study was to discuss the surgical diagnosis and treatment experience of primary hyperparathyroidism. Clinical data of 19 primary hyperparathyroidism patients who were treated surgically in our department from Jan. 2005 to Jul. 2014 were retrospectively analyzed. Besides, general data, clinical manifestations, laboratory and imaging test results, surgical procedures and postoperative follow...

BACKGROUND A variety of stimuli are involved in the pathogenesis of parathyroid gland hyperplasia in renal failure. Recently, it was shown that blocking the signal from the endothelin-1 (ET-1) receptor (ET(A)R/ET(B)R) by a non-selective receptor antagonist, bosentan, reduced parathyroid cell proliferation, parathyroid gland hyperplasia and parathyroid hormone (PTH) levels in normal rats on a ca...

Seventeen patients with parathyroid gland tumors underwent surgical resection at the Hiroshima University Hospital between 1956 and 1988. Three of them where born after the atomic bomb explosion, and 6 of the remaining 14 patients (42.9% of the total- a high proportion) were atomic bomb survivors. Because parathyroid gland tumors and hyperparathyroidism are assumed to develop in patients who ha...

Ultrasonically guided fine needle aspiration of suspect parathyroid tissue to determine parathyroid hormone concentration Since the study of Arima et al,1 several reports have confirmed that enlarged parathyroid glands can be located preoperatively using ultrasound. A general problem has been the difficulty of distinguishing nodular thyroid lesions from enlarged parathyroid glands.2 3 We report...

INTRODUCTION Symptomatic hyperparathyroidism (HPT) refractory to medical management requires surgical intervention with subtotal parathyroidectomy. Primary HPT commonly manifests as a parathyroid adenoma affecting a single gland and can be treated with excision of this single gland. However, secondary HPT in the setting of renal failure or familial diseases often presents with multiglandular hy...

While there is an intimate anatomical and embryological relationship between the inferior parathyroid gland and thymus, concurrent pathology is rare. Three cases have been reported in the literature of a parathyroid adenoma in conjunction with a thymoma. We present a case report of a 60-year-old female with a past medical history of hypercalcemia subsequently found to have primary hyperparathyr...

Secondary hyperparathyroidism is characterised by excessive secretion of parathyroid hormone and parathyroid hyperplasia, resulting in both skeletal and extraskeletal consequences. Recent basic and clinical studies have brought considerable advances in our understanding of the pathophysiology of parathyroid hyperplasia and have also provided practical therapeutic approaches, especially with reg...