We present a new Dutch dysarthric speech database containing utterances of neurological patients with Parkinsons disease, traumatic brain injury and cerebrovascular accident. The speech content is phonetically and linguistically diversified by using numerous structured sentence and word lists. Containing more than 6 hours of mildly to moderately dysarthric speech, this database can be used for ...

Because of continuous changing of anatomy, function and metabolism of the human brain, agerelated change is a major risk factor in most prevalent neurodegenerative diseases, including Parkinsons and Huntingtons disease. Therefore, knowing patterns of age-related atrophy of brain tissue can identify causes and possible role of diseases in decreasing brain function with age. The aim of this study...

Ambulatory monitoring of motor symptoms in Parkinsons disease (PD) can improve our therapeutic strategies, especially in patients with motor fluctuations. Previously published monitors usually assess only one or a few basic aspects of the cardinal motor symptoms in a laboratory setting. We developed a novel ambulatory monitoring system that provides a complete motor assessment by simultaneously...