neurodegenerative disorders such as huntingtons disease, alzheimers disease, parkinsons disease, amyotrophic lateral sclerosis, spinal muscular atrophy, friedreichs ataxia, and others are multi-factorial illnesses in which many pathways (still poorly understood) act serially and in parallel to give a determined pathologic phenotype. thus, presently there are no effective cures for these disease...

a full investigation into the features extracted from voice signals of people with and without parkinson’s disease was performed. a total of 31 people with and without the disease participated in the data collection phase. their voice signals were recorded and processed. the relevant features were then extracted. a variety of feature selection methods have been utilized resulting in a good perf...

Deep brain stimulation (DBS) is an established therapy for the treatment of movement disorders, and has shown promising results for the treatment of a wide range of other neurological disorders. However, little is known about the mechanism of action of DBS or the volume of brain tissue affected by stimulation. We have developed methods that use anatomical and diffusion tensor MRI (DTI) data to ...

Parkinson's disease, also known as movement disorder, is a disorder of the basal ganglia that causes disturbances in and posture but no major paralysis. It has been suggested oxidative stress plays significant part pathogenesis disease. Levodopa replacement therapy dopamine continue to be cornerstones disease treatment. Although levodopa therapy, particular, have ability improve motor symptoms,...

Abstract Introduction Sleep disturbance in patients with Parkinson's disease (PD) is highly prevalent. PD the second most common progressive neurodegenerative disease, affecting about 1% of people over 60 years. Little it's said sleep disorders this which are very frequent and frequently underdiagnosed. In Mexico, there not a lot studies on their population. University Hospital Dr. José E. Gonz...