Parkinson Disease (PD) is a degenerative disease of the extrapyramidal motor system. The formations midbrain are affected and expressed in 1. Tremor, 2. Hypokinesia, 3. Muscle rigidity, 4. Postural instability. Alzheimer's (AD) progressive form senile dementia, leading to complete loss cognitive abilities, developing mainly after 60-65 years age. With these diseases, large number brain structur...

parkinsonism is used to describe a syndrome manifested by any combination of six cardinal features: tremor at rest, rigidity, bradykinesia, loss of postural reflexes, flexed posture and the freezing. decreased dopaminergic neurotransmission in the basal ganglia is the core biochemical pathology in parkinsonism. hereditary parkinsonism includes various heredodegenerative diseases such as hallerv...

Parkinson's, a progressive neural disorder, is difficult to identify due to the hidden nature of the symptoms associated. We present a machine learning approach that uses a definite set of features obtained from the Parkinsons Progression Markers Initiative(PPMI) study as input and classifies them into one of two classes: PD(Parkinson's disease) and HC(Healthy Control). As far as we know this i...

Background: Parkinson’s disease is a progressive neurological disease. Measuring quality of life in these patients could be a useful tool for evaluation and prioritization of care services. The 39-item Parkinson’s Disease questionnaire (PDQ-39) is an acceptable measure to assess quality of life in these patients. Objectives: This study aims to assess the validity and reliability of the Persian ...