A fundamental problem in computational biology is the construction of physical maps of chromosomes from the hybridization experiments between unique probes and clones of chromosome fragments. Double and partial digest problems are two intractable problems used to construct physical maps of DNA molecules in bioinformatics. Several approaches, including exponential algorithms and heuristic algori...

We present a new, practical algorithm to resolve the experimental data in restriction site analysis, which is a common technique for mapping DNA. Specifically, we assert that multiple digestions with a single restriction enzyme can provide sufficient information to identify the positions of the restriction sites with high probability. The motivation for the new approach comes from combinatorial...

HTTP Digest is known to be vulnerable to man-in-the-middle attacks, even when run inside TLS, if the same passwords are used for authentication in some other context without TLS. This is a general problem that affects not just HTTP digest but also other IETF protocols. However, for a class of strong algorithms the attack is avoidable. This document defines version 2 of the HTTP Digest AKA algor...

in this paper, we investigate some problems which can be reduced to the goursat problem for afourth order equation. some results and theorems are given concerning the existence and uniqence for thesolution of the suggested problem.

1. Re-examination of data for the chemical analysis of peptide-bound amino acids in the mesenteric venous blood of anaesthetized guinea-pigs suggests that there are small, but significant, amounts of small peptides in the blood of fasted animals. 2. Furthermore, there is a significant increase in the peptide content of the mesenteric venous blood during intraduodenal infusion of a partial diges...

As mentioned before, we have two approaches for physical mapping: Restriction mapping and mapping by hybridization. We covered restriction mapping previously through the two problems of double digest and partial digest. We now look at mapping by hybridization. While restriction mapping involves the mapping of restriction sites (precise short sequences) of a cutting enzyme based on the lengths o...

HTTP Digest, as specified in RFC 2617, is known to be vulnerable to man-in-the-middle attacks if the client fails to authenticate the server in TLS, or if the same passwords are used for authentication in some other context without TLS. This is a general problem that exists not just with HTTP Digest, but also with other IETF protocols that use tunneled authentication. This document specifies ve...