نتایج جستجو برای: partial thromboplastin time

تعداد نتایج: 2077341  

Journal: :Journal of clinical pathology 1972
J W Estes

Difficulties in evaluating the anticoagulant effect of heparin led to studies of the rate of disappearance of its effect on the whole body partial thromboplastin time, and of its simultaneously bioassayed plasma concentration. The slope of the anticoagulant's dose-effect curve varied with each subject's baseline coagulation status, which probably accounts for the wide range of clinically observ...

2016
Naoki Tokunaga Chihiro Inoue Toshiyuki Sakata Kumiko Kagawa Masahiro Abe Norimichi Takamatsu Takayuki Nakao Toshio Doi

presented in a clearer and more comprehensive way; thus, enabling clinicians to understand the advantages and shortcomings of idarucizumab. Furthermore, as mentioned above, there is a need for an independent prospective randomized trial, which compares current guideline-recommended practices for reversal of dabigatran with idarucizumab in patients with life-threatening bleedings and those requi...

2014
Nicholas J Connors Justin Gill Allison Nakanishi Robert S Hoffman

While we read with great interest the recent report concerning the reversal of dabigatran-induced coagulopathy [1], we are concerned that methodological issues limit the validity of the authors’ conclusions. Firstly, it is unclear why a porcine model was utilized. Although there is clinical relevance for testing reversal agents in a trauma model, all agents were administered ex vivo. Furthermor...

Journal: :Clinical chemistry 1966
J G Lenahan G E Phillips

‘ITHE partial thromboplastin time assay (PTT) as developed by Langdell et al. (1) has proved to be a very usef ul test for studying the coagulatioll mechanism silice it C 11 reveal tile al)SellCe of any factor except Factor VII and platelets. lnder rigorously cOlitrolled COll(litiOlIS, the reproducibility of tile test is satisfactory. However, any change ill tile surface of the svl’inge, test t...

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