We report the development of a micromachined magnetic-bar micromixer for microscale fluid mixing in biological laboratory-on-a-chip applications. The mixer design is inspired by large scale magnetic bar mixers. A rotating magnetic field causes a single magnetic bar or an array of them to rotate rapidly within a fluid environment. A fabrication process of the magnetic bar mixer is developed. Res...

BACKGROUND Bioartificial liver support system (BALSS) based on culturing hepatocytes is an important research field for the treatment of acute liver failure. It is necessary to monitor the state of liver cell functions during the treatment of BALSS in order to guide clinical treatment. OBJECTIVE To design a micro-channel chip to achieve flash mixing for timely detection of liver cell status i...

We developed a confocal microscopic method for a quantitative evaluation of the mixing performance of a three-dimensional microfluidic mixer. We fabricated a microfluidic baker's transformation (MBT) mixer as a three-dimensional passive-type mixer for the efficient mixing of solutions. Although the MBT mixer is one type of ideal mixers, it is hard to evaluate its mixing performance, since the...

A theoretical and experimental study was performed on convective micro mixing in T-shaped micro mixers. In these devices symmetric laminar vortices are developing at low Reynolds numbers Re. The symmetry breaks up with increasing Re numbers. This leads to an enormous enhancement of the mass transfer in the mixing channel. Numerical simulations of the flow characteristics and mixing behaviour ar...

introduction: neurohormones like testosterone and estradiol have an important role in learning and memory. the hippocampus is essentially involved in learning and memory, and is known to be a target for estradiol actions. estrogen receptors (ers) are highly expressed in ca1 of rat hippocampus, and mediate the effects of estrogen on learning and memory. estradiol receptor belong to a family of t...

Abstract In this work, the role of appropriate mixing for mercaptan removal from Kerosene using caustic soda has been investigated in the pilot scale. Static mixer at different condition has been used as a passive mixing tool to achieve proper mixing and consequently high performance of mercaptan removal. Two lengths of static mixer including 20 and 40 cm as well as two pitches 1 and 3 m...

Flows in a microchannel are laminar, which means that mixing depends on only inter-diffusion. A micromixer plays an important role in obtaining fast diagnosis results in the fields of m-TAS (total analysis system), Bio-MEMS and LOC (lab-on-a-chip). In this paper, we propose a new active mixer with vertical flow placement via a series of inlets for micromixing. This has two inlets on the same ax...

The performance of micro-mixers is evaluated in terms of deviations from perfectly mixed state and mixing length (i.e., device length required to achieve perfect mixing). Different variations of T-mixer are reported for improved mixing performance, including geometric constrictions/obstacles embedded in the channel wall, heterogeneously charged walls, grooves on channel base, etc. Most of the r...

Dielectrophoretic (DEP) force, generated by interdigitated electrodes (IDEs), has been utilized to capture bio-particles for microfluidic concentration. However, due to the localized DEP force, DEP-based A -concentrators usually have shallow channels and thus are operated under low flow rates. In this thesis, we propose a mixer-enhanced DEPbased concentrator which can be operate under high flow...