BACKGROUND AND PURPOSE Paradoxical embolization is frequently posited as a mechanism of ischemic stroke in patients with patent foramen ovale. Several studies have suggested that the deep lower extremity and pelvic veins might be an embolic source in cryptogenic stroke (CS) patients with patent foramen ovale. METHODS Consecutive adult patients with ischemic stroke or transient ischemic attack...

Innovation effects on firm value have not been effectively discussed because previous studies ignore the market structure and tax shields from research and development (R&D) (e.g., Hirschey and Weygandt (1985), Shevlin (1991)). Market structures of personal computer (PC) firms are explored in this paper to the degree to which innovation increases firm value depending on market structure charact...

Twin and family studies establish the foundation for studying the genetic, environmental and cultural transmission effects for phenotypes. In this work, we make use of the well established statistical methods and theory for mixed models to assess cultural transmission in twin and family studies. Specifically, we address two critical yet poorly understood issues: the model identifiability in ass...

Correlations between relatives were determined for systolic and diastolic blood pressure. The correlations decrease as age differences between relatives increase in a Norwegian sample with 43,751 parent-offspring pairs, 19,140 pairs of siblings, and 169 pairs of twins. A simple biometric model specifying only age-specific genetic additive effects and environmental effects fitted well to correla...

The analysis of genetic and environmental contributions to preterm birth is not straightforward in family studies, as etiology could involve both maternal and fetal genes. Markov Chain Monte Carlo (MCMC) methods are presented as a flexible approach for defining user-specified covariance structures to handle multiple random effects and hierarchical dependencies inherent in children of twin (COT)...

Recent research has explored the relationships between family and cultural issues, claiming attention on the need to consider and evaluate cultural values and beliefs as useful factors to promote positive family adjustment and parenting outcomes (Cardoso and Thompson, 2010; Taylor et al., 2012). This paper explored self-perception of parental role, family maladjustment and cultural beliefs in a...

The challenge feminist scholarship posed to family studies has been largely met through the incorporation of research on gender dynamics within families and intersectional differences among them. Despite growing attention to gender as performance and power in more diverse families, the more difficult work of understanding the dynamics of change among institutions including the family and using ...

A biometrical genetical analysis of IgG, IgM, and IgA levels in 134 sets of twins is reported. High heritabilities, around .8, are found for all three immunoglobulin levels, and possible reasons for lower heritabilities found in family studies are discussed. There is evidence for genetical dominance tending to decrease IgM and IgA levels, but there is no evidence for the importance of family en...