Cell migration requires a tightly regulated, spatiotemporal coordination of underlying biochemical pathways. Crucial to cell migration is SCAR/WAVE-mediated dendritic F-actin polymerization at the cell's leading edge. Our goal is to understand the role the SCAR/WAVE complex plays in the mechanics of amoeboid migration. To this aim, we measured and compared the traction stresses exerted by Dicty...

The genome of the insect pathogen Photorhabdus luminescens strain TT01 contains numerous genes predicting toxins and proteases. Within the P. luminescens TT01 genome, the products of two loci, plu 4093-plu 4092 and plu 4437-plu 4436, show oral insecticidal activity against both moth and mosquito larvae. The proteins encoded by these loci, here termed 'Photorhabdus insect related' (Pir) proteins...

Multidrug resistance (MDR) of tumour cells is related to the overexpression of ATP-dependent pumps responsible for the active efflux of antitumour agents out of resistant cells. Benzoperimidine and anthrapyridone compounds exhibit comparable cytotoxic activity against sensitive and MDR tumour cells. They diffuse extremely rapidly across the plasma membrane and render the ATP-dependent efflux in...

CLAUDIA CORTI1, WOLFGANG BÖHME2, MASSIMO DELFINO3 & MARCO MASSETI4 Department of Animal Biology and Genetics, University of Florence, Via Romana, 17, I – 50125 Florence, Italy (e-mail: [email protected]) Zoologisches Forschungsinstitut und Museum »Alexander Koenig«, Adeanuerallee 160, D – 53113 Bonn, Germany (e-mail: [email protected]) Vertebrate Paleontology Research Group, ...

Se propone un análisis de los personajes La pira (1972), Óscar Villegas, desde la teoría teatral María del Carmen Bobes Naves. hace una aproximación a relación entre dicha obra y las primeras piezas dramaturgo —El renacimiento (1967), paz buena gente El señor señora (1969)—, para explicar evolución en actantes sinecdóticos —representados con pronombres, números o letras— que dan como resultado ...

ABSTRACT This paper describes the first results obtained by implementing a novel approach to rank vertices in a heterogeneous graph, based on the PageRank family of algorithms and applied here to the bipartite graph of papers and authors as a first evaluation of its relevance on real data samples. With this approach to evaluate research activities, the ranking of a paper/author depends on that ...