نتایج جستجو برای: peak bone mass
تعداد نتایج: 889388 فیلتر نتایج به سال:
In humans, low peak bone mass is a significant risk factor for osteoporosis. We report that LRP5, encoding the low-density lipoprotein receptor-related protein 5, affects bone mass accrual during growth. Mutations in LRP5 cause the autosomal recessive disorder osteoporosis-pseudoglioma syndrome (OPPG). We find that OPPG carriers have reduced bone mass when compared to age- and gender-matched co...
To determine the timing of peak bone mass and density, we conducted a cross-sectional study of bone mass measurements in 265 premenopausal Caucasian females, aged 8-50 yr. Bone mass and bone mineral density were measured using dual X-ray absorptiometry and single-photon absorptiometry at the spine (anteroposterior, lateral), proximal femur, radius shaft, distal forearm, and the whole body. Bone...
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Osteoporosis is a serious skeletal disease causing an increase in morbidity and mortality through its association with age-related fractures. Although most effort in fracture prevention has been directed at retarding the rate of age-related bone loss and reducing the frequency and severity of trauma among elderly people, evidence is growing that peak bone mass is an important contributor to bon...
OBJECTIVE Compare the influence of ethnicity in the prevalence of osteopenia and osteoporosis in various Mexican populations using two normal dual X-ray absorptiometry (DXA) reference databases: manufacturer's incorporating US Hispanic population and a normal mestizo Mexican population. MATERIAL AND METHODS MMP included 9 946 subjects participating in an ongoing long-term cohort study focusin...
The available data indicate that HIV-infected children and adolescents have reduced bone mass compared to healthy peers. The increased survival due to the control of HIV infection by potent antiretroviral treatment, exposes patients to the achievement of a reduced peak bone mass and to an increased fracture risk during adult life. Reduced bone mass in HIV-infected children is the result of alte...
Osteoporosis-related fractures occur more frequently in women compared with men, but mortality is greater in men compared with women. Peak bone mass is a significant predictor of osteoporosis and fracture risk; therefore, it is important to optimize peak bone mass during young adulthood. Several recent longitudinal studies, which are summarized in this article, have investigated bone changes am...
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